True left bundle branch block and long-term mortality in cardiac resynchronisation therapy patients.

CONCLUSIONS: It seems that the Perrin "true LBBB" criteria are not well-suited for selection of CRT candidates. Perhaps they do not reflect the presence of a true/complete LBBB or exclude too many patients who, despite some residual conduction in the left bundle branch, responded well to CRT. PMID: 30799545 [PubMed - as supplied by publisher]
Source: Polish Heart Journal - Category: Cardiology Authors: Tags: Kardiol Pol Source Type: research

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Approximately one third of patients with reduced left ventricular ejection fraction (LVEF) also have electrical mechanical dyssynchrony manifested as widened QRS durations on surface electrocardiogram [1]. The dyssynchronous contraction of the ventricle results in reduced efficiency of cardiac output, functional diastolic mitral regurgitation, and unfavorable progressive remodeling of both the left and right ventricles [2 –4]. Furthermore, QRS prolongation is a significant predictor of clinical deterioration, with increased prevalence of severe mitral regurgitation and increase risk for ventricular tachyarrhythmias, ...
Source: International Journal of Cardiology - Category: Cardiology Authors: Tags: Editorial Source Type: research
CONCLUSION: In our first Asian-Pacific real-world data, automated dynamic CRT optimization showed comparable efficacy to conventional methods regarding clinical outcomes and electromechanical remodeling. PMID: 31293111 [PubMed - in process]
Source: J Korean Med Sci - Category: General Medicine Authors: Tags: J Korean Med Sci Source Type: research
Peripartum cardiomyopathy (PPCM) is a potentially life ‐threatening condition typically presenting as heart failure with reduced ejection fraction (HFrEF) in the last month of pregnancy or in the months following delivery in women without another known cause of heart failure. This updated position statement summarizes the knowledge about pathophysiolo gical mechanisms, risk factors, clinical presentation, diagnosis and management of PPCM. As shortness of breath, fatigue and leg oedema are common in the peripartum period, a high index of suspicion is required to not miss the diagnosis. Measurement of natriuretic peptides,...
Source: European Journal of Heart Failure - Category: Cardiology Authors: Tags: Position Paper Source Type: research
Conclusion: While LVEDD, LVEF, 6MWD, and NYHA were significantly improved in ECHO, ECG, and QuickOpt at 6 months, there were no significant improvements in any of the groups at 12, 24, and 48 months. These findings suggested that the long-term effect of the four CRT methods for heart failure was not significantly different.Cardiology
Source: Cardiology - Category: Cardiology Source Type: research
Cardiac resynchronisation therapy (CRT) has been a cornerstone in the treatment of select advanced heart failure cases since its introduction to our armamentarium in the early 2000s.1 Indeed, 30 –60% of advanced heart failure patients exhibit evidence of dyssynchrony, when defined electrocardiographically or mechanically.2 –4 The latter is a consequence of the former. CRT has several unique features, summarised inTable 1.
Source: Radcliffe Cardiology - Category: Cardiology Authors: Source Type: research
ConclusionsCongestive heart failure is a rare complication in acromegaly-induced cardiomyopathy (occurs in only 3% of patients). Early diagnosis and treatment with curative drugs more than cardiovascular implantable electronic devices might lead to better surgical outcomes in this group of patients.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
linical Cardiology; and Council on Cardiovascular and Stroke Nursing Abstract Left ventricular assist devices (LVADs) are an increasingly used strategy for the management of patients with advanced heart failure with reduced ejection fraction. Although these devices effectively improve survival, atrial and ventricular arrhythmias are common, predispose these patients to additional risk, and complicate patient management. However, there is no consensus on best practices for the medical management of these arrhythmias or on the optimal timing for procedural interventions in patients with refractory arrhythmias. Altho...
Source: Circulation - Category: Cardiology Authors: Tags: Circulation Source Type: research
The objective of this study was to evaluate the relationship between electrocardiogram (ECG) parameters and LVPET in patients with CRT.MethodsIt was an observational, prospective, and monocentric study. From May 2017 to October 2017, all patients who underwent CRT with left quadripolar lead in Rouen University Hospital were included. LVPET was evaluated by echocardiography and defined as the time between the beginning of the QRS and the beginning of pulsed Doppler signal positioned in left ventricular outflow tract in apical view. The following parameters on 12-leads ECG were assessed: QRS width in V3, sum of QRS amplitude...
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
ConclusionsShorter time from onset of QRS to beginning of fragmentation is a simple ECG marker to predict non-responsive patients to CRT.ResumenObjetivoLa terapia de resincronización cardíaca (TRC) es una opción eficaz en el tratamiento de los pacientes con insuficiencia cardíaca y QRS ancho. Se ha demostrado que la presencia de un QRS fragmentado (QRS-f) en el electrocardiograma (ECG) de 12 derivaciones se asocia con una no respuesta a la TRC. El objetivo de este estudio es valorar si la aparición de la fragmentación (intervalo Q-f) es importante en la respuesta a la TRC.Mé...
Source: Revista Clinica Espanola - Category: Internal Medicine Source Type: research
Conclusions: Our patients exhibited a sedentary lifestyle pre- and post-CRT. These findings underscore the need for a cardiac rehabilitation program that encourages post-CRT patients to decrease sedentary time.
Source: Journal of Cardiopulmonary Rehabilitation - Category: Rehabilitation Tags: Brief Reports Source Type: research
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