Endoscopic removal of a gastric pharmacobezoar induced by clomipramine, lorazepam, and domperidone overdose: a case report

ConclusionThis case demonstrates that in the case of a massive drug consumption, a pharmacobezoar should be suspected, particularly when cellulose-coated pills are ingested. Severe poisoning due to delayed drug release from the gastric aggregate is a potential complication. Detection by x-ray is crucial, and treatment is centered on removal of the aggregate. The technique of decontamination varies among experts, and no formal recommendations exist to date. It seems reasonable that endoscopic evaluation should be performed in order to determine the appropriate technique of decontamination. Care should be patient-oriented and take into account the clinical presentation and any organ failure, and it should not be determined solely by the suspected medication ingested. Thus, serum levels are not sufficient to guide management of tricyclic antidepressant intoxication.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research

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Publication date: Available online 14 October 2019Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Marjan Torabi, Ashraf Kazem, Mahshid AbdishahshahaniAbstractObjectiveThe aim of this study is to validate the edited version of FAS for the purpose of couples undergoing ART.Study designIn this cross-sectional study, the validity of the revised version of the FAS questionnaire was assessed by testing it on 212 couples volunteered to undergo ART. The revised version comprises 12 items from the original FAS version and 6 items added based on a survey interview conducted on infertile coup...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
Conclusions The assessment of MS in HF patient-caregiver dyads is important to formulate interventions aimed at improving anxiety and depression in patients and caregivers.
Source: Journal of Cardiovascular Nursing - Category: Nursing Tags: ARTICLES: Heart Failure Source Type: research
In this study, we examined the factors associated with screen time and whether screen time is associated with the physiological and psychosocial health of middle-aged women. We applied a psycho-socioeconomic biobehavioral model of health and studied the outcomes of cardiometabolic biomarkers, insomnia, and quality of life. Methods Secondary data analysis was performed using data from a cross-sectional study conducted with 423 women between 40 and 65 years of age. Socioeconomic, physiological, psychosocial, and behavioral characteristics were measured. Self-reported screen time during the past week was measured using an ...
Source: Journal of Cardiovascular Nursing - Category: Nursing Tags: ARTICLES: Women and Cardiovascular Disease Source Type: research
Background: Metabolic syndrome (MetS), health-related quality of life (HRQL), and depression status are independently associated with cardiac health. Therefore, understanding the associations between MetS, HRQL, and depression status and determining factors related to improved HRQL and depression status in people with MetS may help in cardiovascular disease prevention. Objective: The aim of this study was to examine whether there are differences in HRQL and depression status between Taiwanese women with and without MetS and whether physical activity patterns are associated with HRQL and depression status in this popul...
Source: Journal of Cardiovascular Nursing - Category: Nursing Tags: ARTICLES: Women and Cardiovascular Disease Source Type: research
Conclusion: Half of the patients reported moderate to severe pain at least once during cardiac electrophysiological procedures without analgosedation. However, on average, patients reported only low pain levels. Postinterventional derived data on discomfort reflect the peri-interventional situation.
Source: Journal of Cardiovascular Nursing - Category: Nursing Tags: ARTICLES: Cardiovascular Surgery Source Type: research
This study describes the prevalence of nonmedical methadone use in a community sample of PWID and examines factors associated with recent use of nonmedical methadone. Methods: A cross-sectional sample of PWID (N = 777) was recruited using targeted sampling and interviewed in California (2011-2013). Descriptive, bivariate, and multivariate logistic regression analyses were used to determine characteristics associated with nonmedical methadone use in the last 30 days. To determine if nonmedical methadone use was associated with overdose in the last 6 months, a separate multivariate analysis was conducted...
Source: Substance Use and Misuse - Category: Addiction Tags: Subst Use Misuse Source Type: research
This study aimed to examine if an educational intervention impacted college students' attitudes towards prescription opioid drugs (POD). Methods: Two hundred forty-two participants (72 males, 21 ± 3 years) from an American university participated. After collecting demographic data (questionnaire 1; Q1), investigators recited a narrative in which the protagonist was injured and prescribed POD. Next, participants rated their agreement on 10 Likert prompts and two visual analog scales (VAS) before (Q2) and after (Q3) an educational intervention, then noted (Q4) which topics were most or least influ...
Source: Substance Use and Misuse - Category: Addiction Tags: Subst Use Misuse Source Type: research
Publication date: Available online 14 October 2019Source: SteroidsAuthor(s): Josef Bulant, Martin Hill, Marta Velíková, Anna Yamamotová, Pavel Martásek, Hana Pape┼żováAbstractAnorexia nervosa (AN) is associated with various alterations including the dysfunction of the HPA axis and consequently the hypercortisolemia and deficit in sex hormones but the comprehensive evaluation of changes in circulating steroids during the hospitalization of AN patients is lacking. We investigated the effect of realimentation of women with AN during hospitalization on 45 circulating steroids, the relationshi...
Source: Steroids - Category: Drugs & Pharmacology Source Type: research
Authors: Schanzer B, Rivas-Grajales AM, Khan A, Mathew SJ Abstract Introduction: Generalized anxiety disorder (GAD) is a common and disabling psychiatric condition that affects 3% of the population and exacts significant costs to society if untreated. There are numerous treatment options available, but all have side effects, and none are reliably effective, hence there is a significant need for new medications. Areas Covered: The authors reviewed clinical Phase II and III studies listed on the clinicaltrials.gov and clinicaltrialsregister.eu websites, 2007-present. Additional information was gathered from the study...
Source: Expert Opinion on Investigational Drugs - Category: Drugs & Pharmacology Tags: Expert Opin Investig Drugs Source Type: research
In 1819, a soon-to-be-knighted John Herschel (1792 to 1871) discovered that hyposulfite of soda could “fix” or make photographic images permanent by dissolving away unexposed and otherwise insoluble silver salts. This British genius soon coined terms for his astronomical or botanical images as “negatives” or “positives” and for the art as “photography.” Even after it was renamed sodi um thiosulfate, hyposulfite of soda retained photographers’ nickname for it: “hypo.” An antidote for cyanide poisoning, sodium thiosulfate was supplied in ampoules to physicians...
Source: Anesthesiology - Category: Anesthesiology Source Type: research
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