Off-Label Drugs in Neonatology: Analyses Using Large Data Bases

Two reports in this volume of The Journal from the neonatology team at the University of North Carolina use the Pediatrix Medical Group Data Warehouse of administrative information to further the ongoing discussion of the frequent off-label uses of drugs in the neonatal intensive care unit (NICU).1,2 The report on the frequent, but not approved, use of furosemide for bronchopulmonary dysplasia (BPD) identified that prolonged use can decrease BPD.1 The report on surfactant for preterm infants with or at risk of respiratory distress syndrome (RDS) identified frequent deviations from the Food and Drug Administration (FDA) approved uses.

Source: The Journal of Pediatrics - February 26, 2019 Category: Pediatrics Authors: Alan H. Jobe Tags: Editorial Source Type: research