Chronic cough and obesity

Publication date: Available online 25 February 2019Source: Pulmonary Pharmacology &TherapeuticsAuthor(s): Laurent GuilleminaultAbstractWith respective prevalence of 13% and 9.6%, obesity and chronic cough are two common conditions worldwide. The crucial role of obesity has been highlighted in the development and progression of many respiratory diseases. According to the results of epidemiological studies, obesity, particularly abdominal obesity, may also be associated with chronic cough (CC). CC seems to be more severe in obese patients compared to normal-weight subjects. The management of CC may differ slightly in obese patients compared to non-obese patients. Indeed, asthma and reflux diseases, which are considered key factors in the onset of CC, are characterised by more severe symptoms in obese patients. Asthma is associated with a resistance to usual treatments in obese patients but no data are available on the effect of inhaled therapies in obese subjects with cough variant asthma. Other emergent causes of CC have been reported in obese patients. Obstructive sleep apnoea and diabetes may also be involved in the development of CC and should be taken into account in obese patients with CC. The beneficial effect of weight loss on chronic cough has been suggested.
Source: Pulmonary Pharmacology and Therapeutics - Category: Respiratory Medicine Source Type: research

Related Links:

Antipsychotic medications are a vital part of controlling psychosis in schizophrenic patients. However, when those patients live in nursing facilities, we are obligated by CMS to undertake gradual dose reductions of antipsychotic medication if possible. Sometimes, these efforts are successful and sometimes they fail. Antipsychotic medications have many side effects, including sedation, diabetes, hyperlipidemia, weight gain, motor rigidity, impaired gait, and falls. Monitoring of blood glucose, lipids, and extrapyramidal symptoms is mandatory.
Source: Journal of the American Medical Directors Association - Category: Health Management Authors: Source Type: research
Management of diabetes in post-acute settings needs special considerations. Hypoglycemia in the skilled nursing and rehabilitation facilities can lead to readmissions and complications including falls. Current EHR care-sets may not make a distinction between hospital and post-acute settings regarding diabetes management. The current diabetes management care-set in the EHR of our large healthcare system includes checking the blood sugar QID/AC/HS (before breakfast, lunch and dinner, and bedtime).
Source: Journal of the American Medical Directors Association - Category: Health Management Authors: Source Type: research
The geriatric population is at high risk of severe low blood glucose (LBG) events due to diminished homeostatic mechanisms, especially on hypoglycemic medications. Moderate to severe LBG events in these patients can contribute to behavior changes such as agitation, change in level of consciousness, disruption of sleep, instability and increased risk of myocardial infarction, stroke and falls. Rapid recognition and appropriate treatment and prevention of LBG and recurrences can reduce risk for hospitalization in the geriatric population.
Source: Journal of the American Medical Directors Association - Category: Health Management Authors: Source Type: research
CONCLUSIONS.: Our results confirm the multidimensional nature of mania. Hyperactivity, increased speech, and thought disorder appear as core features of the clinical construct. The mood experience could be heterogeneous, depending on the co-occurrence of euphoric (elevated mood) and dysphoric (irritability and depressive mood) emotions of varying intensity. Results are also discussed regarding their relationship with other constitutive elements of bipolar disorder, such as mixed and depressive states. PMID: 32093802 [PubMed - in process]
Source: Journal of the Association of European Psychiatrists - Category: Psychiatry Tags: Eur Psychiatry Source Type: research
Authors: Lee YM, Park SH, Lee DH Abstract OBJECTIVE: The aim of this paper is to propose a new hypothesis for the role of lipophilic chemical mixtures stored in adipose tissue in the development of dementia. Specifically, we present how the dynamics of these chemicals can explain the unexpected findings from the Action for Health in Diabetes (Look AHEAD) study, which failed to show long-term benefits of intentional weight loss on cognition, despite substantial improvements in many known risk factors for dementia. Moreover, we discuss how the role of obesity in the risk of dementia can change depending on the dynami...
Source: The Journal of Alzheimers Association - Category: Psychiatry Tags: Alzheimers Dement Source Type: research
Source: Journal of Renal Nutrition - Category: Urology & Nephrology Source Type: research
Publication date: Available online 25 February 2020Source: Evaluation and Program PlanningAuthor(s): Tanis J. Walch, Richard R. Rosenkranz, Michaela A. Schenkelberg, Bronwyn S. Fees, David A. Dzewaltowski
Source: Evaluation and Program Planning - Category: International Medicine & Public Health Source Type: research
Publication date: Available online 25 February 2020Source: The Lancet Respiratory MedicineAuthor(s): Jaclyn A Smith, Michael M Kitt, Alyn H Morice, Surinder S Birring, Lorcan P McGarvey, Mandel R Sher, Yu-Ping Li, Wen-Chi Wu, Zhi Jin Xu, David R Muccino, Anthony P Ford, Jaclyn Smith, Lorcan McGarvey, Surinder Birring, James Hull, Warner W Carr, Alan B Goldsobel, Gary N Gross, John R Holcomb, Iftikhar Hussain
Source: The Lancet Respiratory Medicine - Category: Respiratory Medicine Source Type: research
Publication date: Available online 25 February 2020Source: The Lancet Respiratory MedicineAuthor(s): Richard S Irwin, Cynthia L French, J Mark Madison
Source: The Lancet Respiratory Medicine - Category: Respiratory Medicine Source Type: research
Publication date: Available online 25 February 2020Source: NeuroImage: ClinicalAuthor(s): Bart van den Munckhof, Anne F. Zwart, Lauren C. Weeke, Nathalie H.P. Claessens, Joost D.J. Plate, Alexander Leemans, Hugo J. Kuijf, Heleen C. van Teeseling, Frans S.S. Leijten, Manon J.N. Benders, Kees P.J. Braun, Linda S. de Vries, Floor E. Jansen
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
More News: Asthma | Cough | Diabetes | Drugs & Pharmacology | Eating Disorders & Weight Management | Endocrinology | Epidemiology | Obesity | Obstructive Sleep Apnea | Respiratory Medicine | Sleep Disorders | Sleep Medicine | Study | Weight Loss