Cochrane's 30 under 30: Shalini Suresh

Cochrane is made up of  13,000 members and over 50,000 supporters come from more than 130 countries, worldwide. Our volunteers and contributors are researchers, health professionals, patients, carers, people passionate about improving health outcomes for everyone, everywhere.Cochrane is an incredible community of people who all play their part in improving health and healthcare globally. We believe that by putting trusted evidence at the heart of health decisions we can achieve a world of improved health for all.  Many  of our contributors are young people working with Cochrane as researchers, citizen scientists, medical students, and volunteer language translators and we want to recognize the work of this generation of contributors as part of this series called, Cochrane’s “30 under 30. "  In this series, we will interview 30 young people, 30 years old or younger who are contributing to Cochrane activities in a range of ways, all promoting evidence-informed health decision making across the world.  We will be hearing from them in a series of interviewees published over the coming months.We're keen to hear from you. Would you like to take part in this series? Do you know someone you'd like to see interviewed? Contact  Or if you want to know more about Cochrane’s work contact where our community support ...
Source: Cochrane News and Events - Category: Information Technology Authors: Source Type: news

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This study analysed the prevalence of cervical spine instability in Rheumatoid Arthritis (RA) patients following at a single centre in Basrah.Patients and methodsData were collected directly from patients through cervical spine examinations. Each patient was sent for dynamic (flexion and extension) lateral cervical radiographic imaging to assess the presence of atlantoaxial subluxation (AAS), superior migration of the odontoid (SMO) and sub-axial subluxation (SAS). Patients with positive radiographic findings were sent for MRI scans of the cervical spine to assess neurological compression.ResultsThe prevalence rate of cerv...
Source: Journal of Clinical Orthopaedics and Trauma - Category: Orthopaedics Source Type: research
Conclusion: Imaging of 64Cu-GPVI-Fc accumulation in the ECM matrix appears to be a promising candidate for monitoring chronic inflammation. By binding to exposed fibrous tissue (collagen, fibronectin, etc.) after extravasation, a new insight is provided into the fibrotic events resulting from a prolonged inflammatory state.
Source: Theranostics - Category: Molecular Biology Authors: Tags: Research Paper Source Type: research
Authors: Tetikkurt C, Inci N, Yanardag H Abstract A 63-year-old male presented with loss of appetite, subfebrile fever, swelling of the right hand and dyspnea on exertion for three months. Past medical history revealed methotrexate treatment of six months for rheumatoid arthritis. Chest radiography and computed tomography (CT) revealed diffuse miliary nodules. PET/CT scan demonstrated diffuse FDG uptake in both lungs, in the spleen, in the right hand, the mediastinal and the axillary lymph nodes. MR of the right hand showed inflammatory arthritis. Histopathology of the right hand tru-cut biopsy revealed degenerativ...
Source: Monaldi Archives for Chest Disease - Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research
Conclusion: sCD25 is a sensitive serum marker to evaluate RA disease activity, and it could be a promising laboratory marker to assist RA disease activity assessment in patients with active RA but negative ESR or CRP. PMID: 31159626 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Rheumatology - Category: Rheumatology Authors: Tags: Scand J Rheumatol Source Type: research
A 52-Year-Old Woman With an Abdominal Mass, Bilateral Pulmonary Nodules, and Mediastinal and Hilar Lymphadenopathy. Chest. 2019 Jun;155(6):e175-e178 Authors: Van Treeck BJ, Gehlbach DA, Foster GH, Utz JP, Aubry MC, Colby TV, Yi ES Abstract CASE PRESENTATION: A 52-year-old, nonsmoking, African-American woman with a history of obesity, hypertension, and rheumatoid arthritis was referred for workup of multiple bilateral pulmonary nodules. The pulmonary nodules were discovered incidentally while undergoing a CT scan for an abdominal mass that was radiographically diagnosed as a uterine leiomyoma. She...
Source: Chest - Category: Respiratory Medicine Authors: Tags: Chest Source Type: research
Conclusion: Sick leave and improved worker productivity were mainly predicted by non-disease-specific variables. Both outcomes can be predicted on a 3 month basis, using the outcome over the past 3 months for the next 3 months. By applying this model in daily practice, decisions for therapy change could be based not solely on disease activity but also taking into account a possible high risk for sick leave in the upcoming 3 months. PMID: 31135239 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Rheumatology - Category: Rheumatology Authors: Tags: Scand J Rheumatol Source Type: research
Conclusions: Our findings indicate that global assessment with NaF-PET/CT is a powerful imaging technique in detecting and quantifying molecular calcification in the abdominal aorta. FDG TBRmean did not show a significant difference between the two groups indicating the low sensitivity of FDG PET in detecting and characterizing atherosclerotic plaques. Further studies are needed to confirm the potential role of NaF to diagnose, monitor and assess the treatment response in patients at high risk for atherosclerosis.
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Cardiovascular Clinical Science Posters Source Type: research
Conclusions: IV administration of TCT was well-tolerated and demonstrated joint-specific localization in RA subjects, revealing potentially significant immunodiagnostic information about CD206-expressing synovial macrophage involvement in RA patients. Additionally, increased TCT activity via IV administration may enhance localization and anatomic delineation in tilmanocept-positive joints of RA patients compared to SC administration studied in a prior Phase I trial. Study data analysis revealed an optimal mass dose of 134 µg of tilmanocept radiolabeled with 10 mCi Tc 99m with an imaging time frame of 1-3 hours post i...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Musculoskeletal Source Type: research
Conclusions: NaF-PET/CT scan appears to be a valuable imaging approach in evaluating the metabolic activity in osseous structures of the TMJ in RA patients. The degree of NaF uptake in the TMJ correlated with biochemical parameters of disease severity based on DAS28-CPR and DAS28-ESR scores.
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Data Analysis & amp; Management Posters Source Type: research
Conclusions: RA patients appear to have significantly higher metabolic activity in the TMJ than age/ gender matched healthy control subjects. Our results illustrate the potential value of using FDG-PET/CT for evaluation of TMJ disorders and suggest that this modality may be applied for monitoring effects of treatment regimens.
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Data Analysis & amp; Management Posters Source Type: research
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