Surgical Treatment for Congenital Heart Defects in Down Syndrome Patients

Conclusion: Surgical treatment in patients with CHD and DS usually does not require highly complex surgical procedures, but are affected by infectious complications, resulting in a longer ICU and h ospital length of stay with considerable mortality.
Source: Revista Brasileira de Cirurgia Cardiovascular - Category: Cardiovascular & Thoracic Surgery Source Type: research

Related Links:

This study investigated the fixation stability of four different tibial fixations for the meniscal root sutures. Twenty-four porcine tibiae with intact medial meniscus roots were randomly assigned into four groups: transosseous suture, washer, suture anchor or screw with washer. Each sample underwent cyclic loading followed by a load-to-failure test. The maximum average load and displacement at failure for each of the repair groups were as follows: transosseous suture, 232.8 ​N and 12.16 ​mm; washer, 189.9 ​N and 21.5 ​mm; suture anchor, 140.6 ​N and 13.8 ​mm and screw with washer,...
Source: Journal of Orthopaedic Translation - Category: Orthopaedics Source Type: research
ConclusionsThe novel success scale for evaluating alveolar cleft repair using CBCT takes into consideration all dimensions of the bony bridge. Future application is necessary for validation of its potential value.
Source: Journal of Cranio Maxillofacial Surgery - Category: ENT & OMF Source Type: research
Publication date: Available online 17 February 2020Source: American Journal of OtolaryngologyAuthor(s): Nanditha Srinivasa, Gopalakrishnan Suriyanarayanan
Source: American Journal of Otolaryngology - Category: Endocrinology Source Type: research
HEART ATTACKS are often caused by coronary heart disease, and risk of developing this is increased by a high-fat diet, high cholesterol and being overweight or obese. Research in the past has found a link between eating certain foods and heart disease, but a new study has confirmed a popular breakfast food is not as bad as first though.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Conclusion: The prevalence of CHD in patients with Down syndrome is similar between Malaysia and high-income countries. The lower survival rate is attributed to limited expertise and resources which limit timely surgery.What is Known:•The survival of patients with Down syndrome with congenital heart disease (CHD) has improved in high-income countries. However, little is known about the survival of patients with Down syndrome with CHD from middle-income countries.•In the Caucasian population, atrioventricular septal defect is the most common type of CHD associated with Down syndrome.What is New:•In middle-inc...
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research
Down syndrome (DS) is one of the most common chromosomal abnormalities. The incidence of DS at birth in developed countries has remained relatively stable over the last 20 years, at approximately 1 per 1000 live births. DS is associated with a number of congenital defects and is also at increased risk of conditions that may develop later in life, and thus requires multidisciplinary care and close surveillance. Congenital heart disease (CHD) is present in 35%–50% of patients and is haemodynamically significant in two-thirds.1 Early diagnosis and treatment in expert centres are essential for improving short-term a...
Source: Heart - Category: Cardiology Authors: Tags: Congenital heart disease, Drugs: cardiovascular system, Hypertension, Interventional cardiology, Epidemiology Editorials Source Type: research
Objective To characterise patients with trisomy 21 (Down syndrome, DS) based on the data of the German National Register for Congenital Heart Defects, to identify changes in the availability of surgical therapy over time and to analyse the impact of these changes on developing Eisenmenger syndrome (ES) as well as survival. Methods Out of 1549 patients with DS with congenital heart disease in the National Register for Congenital Heart Defects, 894 patients (55% female, mean age 17.5 years) had a post-tricuspid shunt lesion (atrioventricular septal defect 69.5%, ventricular septal defect 27.7%, patent arterial duct 2.6...
Source: Heart - Category: Cardiology Authors: Tags: Congenital heart disease in adult patients, Congenital heart disease, Drugs: cardiovascular system Source Type: research
CONCLUSION: Our study confirmed that the profile and type of CHD in DS in the Moroccan setting exhibited slight differences in the distribution of these CHDs compared with European neighbours and other Western countries. Further studies are needed to determine which variables have an impact on these differences. PMID: 27805241 [PubMed - in process]
Source: Cardiovascular Journal of Africa - Category: Cardiology Authors: Tags: Cardiovasc J Afr Source Type: research
CONCLUSION: The frequency of CHD in our DS cohort is comparable with Europe, Asia ,and other KSA regions. However its pattern appears to be different from some areas in KSA. PMID: 27381537 [PubMed - in process]
Source: Saudi Medical Journal - Category: Middle East Health Tags: Saudi Med J Source Type: research
CONCLUSION: The high prevalence of congenital heart disease among the patients at the Down syndrome outpatient clinic (50%) was similar to findings from other studies and justifies investigation during the neonatal period, so as to decrease mortality and morbidity. PMID: 26648279 [PubMed - as supplied by publisher]
Source: Sao Paulo Medical Journal - Category: Journals (General) Authors: Tags: Sao Paulo Med J Source Type: research
More News: Atrioventricular Septal Defect | Cardiology | Cardiovascular | Cardiovascular & Thoracic Surgery | Databases & Libraries | Down's Syndrome | Gastroschisis Repair | Heart | Heart Disease | Hole in the Heart | Intensive Care | Perfusion | Study | Ventricular Septal Defect