GSE123495 Malaria Host Pathogen Interaction Center Experiment 30: Pilot experiment for Macaca mulatta infected with Plasmodium knowlesi Malayan strain sporozoites to produce and integrate measures of acute primary infection.

Contributors : John W Barnwell ; Steven E Bosinger ; Monica Cabrera-Mora ; Regina J Cordy ; Jeremy D DeBarry ; Mary R Galinski ; Allison Hankus ; Jay C Humphrey ; Nicolas Lackman ; Stacey A Lapp ; Alberto Moreno ; Mustafa Nural ; Suman B Pakala ; Nirav Patel ; Chester J Joyner ; Mariko S Peterson ; Gregory K TharpSeries Type : Expression profiling by high throughput sequencingOrganism : Macaca mulatta ; Plasmodium knowlesiThis project is part of the Malaria Host-Pathogen Interaction Center (MaHPIC) - a transdisciplinary malaria systems biology research program initially supported by an NIH/NIAID contract (# HHSN272201200031C, 2012-2017; see http://www.systemsbiology.emory.edu). The MaHPIC has continued with support from the Defense Advanced Research Project Agency (DARPA) and others. The MaHPIC generates many data types (e.g., clinical, hematological, parasitological, metabolomics, functional genomics, lipidomics, proteomics, immune response, telemetry) and mathematical models, to iteratively test and develop hypotheses related to the complex host-parasite dynamics in the course of malaria in non-human primates (NHPs), and metabolomics data via collaborations with investigators conducting clinical studies in malaria endemic countries, with the overarching goal of better understanding human disease, pathogenesis, and immunity. Curation and maintenance of all data and metadata are the responsibility of the MaHPIC.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Macaca mulatta Plasmodium knowlesi Source Type: research