Long non-coding RNA LINC00968 attenuates drug resistance of breast cancer cells through inhibiting the Wnt2/ β-catenin signaling pathway by regulating WNT2.

CONCLUSION: Collectively, overexpressed LINC00968 contributes to reduced drug resistance in breast cancer cells by inhibiting the activation of the Wnt2/β-catenin signaling pathway through silencing WNT2. This study offers a new target for the development of breast cancer treatment. PMID: 30791958 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/30791958?dopt=Abstract

Source: Clinical Breast Cancer - February 21, 2019 Category: Cancer & Oncology Authors: Xiu DH, Liu GF, Yu SN, Li LY, Zhao GQ, Liu L, Li XF Tags: J Exp Clin Cancer Res Source Type: research