Recombinant H5 hemagglutinin adjuvanted with nanoemulsion protects ferrets against pathogenic avian influenza virus challenge.
CONCLUSION: Intranasal immunization with rH5 antigen formulated with NE01 adjuvant elicited strong, broad and balanced immune responses that effectively protect against H5N1 influenza virus infection in the ferret model. The ease of formulation of rH5-NE01 makes this novel combination a promising mucosal vaccine candidate for pandemic influenza.
PMID: 30795941 [PubMed - as supplied by publisher]
Source: Vaccine - Category: Allergy & Immunology Authors: Wang SH, Smith D, Cao Z, Chen J, Acosta H, Chichester JA, Yusibov V, Streatfield SJ, Fattom A, Baker JR Tags: Vaccine Source Type: research
More News: Bird Flu | Bird Flu (H5N1 Avian Influenza) Vaccine | Flu Pandemic | H5N1 | Influenza | Influenza Vaccine | Nanotechnology | Pandemics | Vaccines | Veterinary Vaccinations | Weight Loss