GSE78267 Altered cell signaling in the absence of Dynamin function: a transcriptomic approach from yeast to humans (yeast)

Contributors : Macarena Morillo-Huesca ; Maria S Dominguez-Sanchez ; Tatiana Alfonso-Perez ; Monica Perez-Alegre ; Eloisa Andujar ; Valentina Bachetti ; Mario Garcia-Dominguez ; Jose C ReyesSeries Type : Expression profiling by arrayOrganism : Saccharomyces cerevisiae ; Schizosaccharomyces pombeDynamins are large multidomain GTPases involved in membrane scission. We have investigated the transcriptional consequences of deleting Vps1, a DNM2 homologue, in the yeast Saccharomyces cerevisiae. Interestingly, the vps1 ∆ mutation causes strong transcriptional defects also in yeast.Data suggest that DNM2 and Vps1 play an essential regulatory role connecting several membrane-related processes including endocytosis, lipid homeostasis and different signal transduction pathways.

Source: GEO: Gene Expression Omnibus - February 24, 2019 Category: Genetics & Stem Cells Tags: Expression profiling by array Saccharomyces cerevisiae Schizosaccharomyces pombe Source Type: research