Advanced DNA fingerprint genotyping based on a model developed from real chip electrophoresis data.

This study presents a new approach based on global multiple alignments of bands of all samples, with an adaptive threshold derived from the detailed migration analysis of a large number of real samples. The proposed approach allows the accurate automated analysis of DNA fingerprint similarities for extensive epidemiological studies of bacterial strains, thereby helping to prevent the spread of dangerous microbial infections.
PMID: 30788173 [PubMed]

Source: Adv Data - February 24, 2019 Category: Epidemiology Authors: Skutkova H, Vitek M, Bezdicek M, Brhelova E, Lengerova M Tags: J Adv Res Source Type: research