Mineralocorticoid Antagonism and Vascular Function in Early Autosomal Dominant Polycystic Kidney Disease: A Randomized Controlled Trial

Conclusions24 weeks of aldosterone antagonism reduced systolic blood pressure without changing vascular function in patients with early-stage ADPKD.FundingNIDDK, NIH National Center for Advancing Translational Sciences, and the Zell Family Foundation.Trial RegistrationRegistered at ClinicalTrials.gov with study number NCT01853553.
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research