Mimickers of neuropsychiatric manifestations in systemic lupus erythematosus

Publication date: Available online 22 February 2019Source: Best Practice & Research Clinical RheumatologyAuthor(s): Jaqueline Cristina de Amorim, Aline Kuhl Torricelli, Renan Bazuco Frittoli, Aline Tamires Lapa, Sergio San Juan Dertkigil, Fabiano Reis, Lilian TL. Costallat, Marcondes Cavalcante França Junior, Simone AppenzellerAbstractSystemic lupus erythematosus (SLE), presenting with new onset or worsening neuropsychiatric (NP) symptoms, is a challenge in clinical practice. Mimickers such as infections, drug-induced side effects, metabolic abnormalities, malignancies, and alcohol-related disorders have to be excluded, before attributing the manifestations to disease activity. Proper diagnosis is essential to guide adequate management and reduce morbidity and mortality. In this review article, we will highlight clinical, laboratorial, and neuroradiological features that are helpful to assist in the differential diagnosis.
Source: Best Practice and Research Clinical Rheumatology - Category: Rheumatology Source Type: research