Mechanisms of Metastasis and Cell Mobility - The Role of Metabolism.

Mechanisms of Metastasis and Cell Mobility - The Role of Metabolism. Geburtshilfe Frauenheilkd. 2019 Feb;79(2):184-188 Authors: Gründker C, Läsche M, Hellinger JW, Emons G Abstract Tumour metastasis is responsible for more than 90% of tumour-associated mortality. About one third of breast cancer patients in the early stage develop metastases. The transformation in tumour development referred to as the "metastatic cascade" or "metastatic cycle" is a complex and multi-stage event. While it is generally recognised that epithelial-mesenchymal transformation (EMT) plays a crucial role in cancer progression and metastasis, the metabolic events in this process have received little attention to date. We would therefore like to provide a brief overview here of the influence of the metabolism on the progression and metastasis of tumours. PMID: 30792548 [PubMed]
Source: Geburtshilfe und Frauenheilkunde - Category: OBGYN Tags: Geburtshilfe Frauenheilkd Source Type: research