03:18 PM Abstract No. 15 Lutonix below-the-knee global drug-coated balloon IDE study: primary endpoint outcomes at 6 months and safety subgroup analyses

The most common clinical presentation of peripheral artery disease (PAD) comprises intermittent claudication though about one third of patients will progress to below-the-knee critical limb ischemia. Currently, percutaneous transluminal angioplasty (PTA) is the standard endovascular therapy employed in this patient population. The Lutonix BTK  IDE multicenter randomized study was conducted to assess the safety and efficacy of the Lutonix DCB for the treatment of stenosis or occlusion of native below-the-knee arteries.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Scientific Session 2: Finish the Race Source Type: research

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Introduction: The study examines the effect of a cross-sectoral rehabilitation programme versus usual care for patients conservatively treated for intermittent claudication (IC). Peripheral Artery Disease is one of the most prevalent cardiovascular diseases (1). The most common symptom is IC, defined as a cramping leg pain that occurs during walking and is relieved by a short period of rest. Patients with IC have diminished walking capacity, restricted activity and mobility and reduced health-related quality of life.
Source: European Journal of Vascular and Endovascular Surgery - Category: Surgery Authors: Source Type: research
CONCLUSIONS: The current study analyzed nationwide procedural databases and demonstrated the presentation pattern of symptomatic PAD and CAD warranting revascularization. PMID: 31748468 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - Category: Cardiology Tags: J Atheroscler Thromb Source Type: research
In the last decades, due to aging communities and worse risk factor profiles, incidences of peripheral artery disease (PAD) increased both in western and developing countries and are predicted to drastically increase globally in the next years [1,2]. Yet, PAD remains still highly undetected [3]. Moreover, definitions and diagnostic assessment of PAD widely differ in the current literature. Clinicians will agree that comparability between intermittent claudication (IC) and a low ankle-brachial index (ABI
Source: Atherosclerosis - Category: Cardiology Authors: Tags: Editorial Source Type: research
Critical limb ischemia (CLI) is the clinical manifestation of severe peripheral artery disease presenting as rest pain (RP), and tissue loss (TL). Most studies compare CLI as a homogenous group with claudication with limited database studies specifically studying these differences. We hypothesize that CLI should be stratified into RP and TL because of significant differences in disease severity, comorbidities, and outcomes.
Source: Annals of Vascular Surgery - Category: Surgery Authors: Tags: Clinical Research, Basic Science Source Type: research
Supervised exercise therapy (SET) is an inexpensive, low-risk, and effective option when compared with invasive therapies for the treatment of patients with peripheral artery disease (PAD) and intermittent claudication. Randomized, controlled trials have demonstrated the benefits of SET in improving maximum walking distance in intermittent claudication patients, and society guidelines recommend SET as first-line therapy. In 2017, the Centers for Medicare&Medicaid Services (CMS) added coverage of SET.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Source Type: research
A 77-year-old female with peripheral artery disease underwent brachiocephalic artery stenting for right upper extremity claudication. Given a very high atherosclerotic burden seen on CT, a dual-filter embolic protection device (Sentinel, Boston Scientific) was deployed from the right radial artery to protect the right common carotid and subclavian arteries, and therefore the vertebral artery, during the stenting procedure. This case report demonstrates a novel use of this dual-filter device to provide both carotid and vertebral artery embolic protection during brachiocephalic artery intervention.
Source: Annals of Vascular Surgery - Category: Surgery Authors: Tags: Case Report Source Type: research
Conclusion: The patterns of physical activity of PAD patients are characterized by a large amount of time spent in sedentary behaviors and a low engagement in MVPA. Younger patients, regardless of the clinical and functional factors, were more likely to meet the current physical activity recommendations.Resumo Fundamento: Aumentos nos n íveis de atividade física diária são recomendados para pacientes com doença arterial periférica (DAP). No entanto, apesar dessa recomendação, pouco se sabe sobre os padrões de atividade física dos pacientes com DAP. Objet...
Source: Arquivos Brasileiros de Cardiologia - Category: Cardiology Source Type: research
Conclusion: The patterns of physical activity of PAD patients are characterized by a large amount of time spent in sedentary behaviors and a low engagement in MVPA. Younger patients, regardless of the clinical and functional factors, were more likely to meet the current physical activity recommendations.Resumo Fundamento: Aumentos nos n íveis de atividade física diária são recomendados para pacientes com doença arterial periférica (DAP). No entanto, apesar dessa recomendação, pouco se sabe sobre os padrões de atividade física dos pacientes com DAP. Objet...
Source: Arquivos Brasileiros de Cardiologia - Category: Cardiology Source Type: research
Conditions:   Peripheral Vascular Disease;   Intermittent Claudication;   Walking, Difficulty;   Critical Limb Ischemia;   Ischemia Limb Interventions:   Device: Active FlowOx™;   Device: Sham FlowOx™ (Placebo) Sponsors:   Otivio AS;   mediq Innovation Experts GmbH;   Hannover Medical School Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conclusions: The adoption of ME in 2014 was associated with significant increase in the use of infrainguinal bypass for nonsevere and elective cases, along with improved in-hospital mortality and MALE at 1 year. Longer follow-up is needed to evaluate the impact of ME on other aspects of care and longer term outcomes of PAD patients.
Source: Annals of Surgery - Category: Surgery Tags: PAPERS OF THE 139TH ASA ANNUAL MEETING Source Type: research
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