Bilateral ICA block: MRI
Case Report 76 yrs old female pt. presets for MR brain angio with c/o giddiness of long duration.MRA shows– marked narrowing&grossly reduced flow signal of both ICA in carotid canal with complete absence of cavernous ICA with source images suggesting right PCOM feeding ipsilateral MCA& left MCA possibly filling from right side. Both MCA are grossly reduced in caliber with origins not identified along with poorly visualized both ACA&ACOM.Dominant grossly tortuous&atheromatous vertebral system with basilar artery suggesting tortuosity/atheromatous looping / redundancy with both PCA normal for the age.Multiple tiny possible collaterals identified in the basal ganglia (right> left) along with external carotid branches possibly feeding Circle of Willis branches predominantly MCA. Brain parenchyma shows possible gliosis post infarction in right frontal lobe&multiple ill defined irregular T2/FLAIR hyperintensities in both gangliocapsular&periventricular whitematter suggesting old infarctions with rest of brain&CP angles unremarkable for the age.Submitted by Dr MGK Murthy, Dr GA PrasadClinical features of ICA occlusion range from asymptomatic to acute stroke or death, transient monocular blindness ( amourosis fugax), orthostatic TIA / post prandial hypotension, exercise induced ischemic symptoms ( cerebral claudication), involuntary limb shaking, headache ( due to collateral circulation) , syncope , dementia.P...
Publication date: Available online 4 April 2020Source: Journal of Geriatric OncologyAuthor(s): Claire A. Surr, Rachael Kelley, Alys W. Griffiths, Laura Ashley, Fiona Cowdell, Ann Henry, Michelle Collinson, Ellen Mason, Amanda J. Farrin
Conclusions: In the current study, the prevalence of depression among diabetic outpatients was higher than that of studies conducted in other settings. Depression was significantly associated with female sex, rural residency, type 2 diabetes mellitus, duration of illness> 6 years, high fear of complications, and poor social support. PMID: 32243106 [PubMed - as supplied by publisher]
CONCLUSIONS By downregulating expression of the SNHG5 gene and then altering expression of the TGR5 gene, the damage to colorectal cells induced by high glucose was alleviated. This may be one of the mechanisms underlying the effect of sleeve gastric surgery in treatment of diabetes mellitus. PMID: 32242546 [PubMed - in process]
This study was an open-label, parallel controlled study. Patients were included if they were newly diagnosed with type 2 diabetes (
CONCLUSIONS In this study, we screened 104 lncRNA therapeutic targets and several signaling pathways (Wnt, PPAR, amino acid metabolism signaling pathway, mTOR, and lipid metabolism-related pathways) of liraglutide against T2DM based on lncRNA sequencing. PMID: 32238798 [PubMed - in process]
CONCLUSIONS A prognostic model based on six variables was predictive for incident type 2 diabetes mellitus and prediabetes in a healthy population in Japan. PMID: 32235819 [PubMed - in process]
Authors: Oliveira R, Teodoro T, Botelho A PMID: 32238246 [PubMed - in process]
CONCLUSION: The current study showed that man gender, diabetes and hypertension were the greatest risk factors for PAD. We conclude that man patients with diabetes and/or hypertension should be put under serious consideration for routine CTA examination when under evaluation for LSS and intermittent claudication. PMID: 32242344 [PubMed - in process]
Abstract Polymyalgia rheumatica and Giant Cell Arteritis - Update on Diagnosis and Therapy Abstract. Polymyalgia rheumatica (PMR) is an inflammatory syndrome which often co-incides with giant cell arteritis (GCA). Due to unspecific symptoms and a plethora of possible alternative diagnoses, PMR often represents a diagnostic challenge. The use of ultrasound, but also other imaging methods has improved and accelerated the time to diagnosis in PMR and GCA, so that complications such as blindness can be reduced. Glucocorticoids are still the main initial therapy for both diseases. Although further research is needed co...
PMID: 32242338 [PubMed - in process]
More News: Blindness | Blogging | Brain | Cardiology | Cardiovascular | Carotid Endarterectomy | Dementia | Diabetes | Endocrinology | Headache | Heart | Hypertension | Intermittent Claudication | Ischemic Stroke | Migraine | Neurology | Opthalmology | Perfusion | Radiology | Smokers | Sports Medicine | Stroke