Comparison of Rosuvastatin Versus Atorvastatin for Coronary Plaque Stabilization

Statins are widely used to lower cholesterol and to reduce cardiovascular events. Whether all statins have similar effects on plaque stabilization is unknown. We aimed to investigate coronary plaque response to treatment with different statins that result in similar lipid reduction using serial multimodality intracoronary imaging. Patients with de novo coronary artery disease requiring intervention were randomized to rosuvastatin 10mg (R10) or atorvastatin 20mg (A20) daily. Optical coherence tomography (OCT) and intravascular ultrasound (IVUS) were performed at baseline, 6 months, and 12 months.
Source: The American Journal of Cardiology - Category: Cardiology Authors: Source Type: research