miRNA-21 promotes osteogenesis via the PTEN/PI3K/Akt/HIF-1 α pathway and enhances bone regeneration in critical size defects

Functional reconstruction of maxillofacial bone defects is a considerable clinical challenge. Many studies have emphasized the osteogenic and angiopoietic abilities of stem cells for tissue regeneration. We pr...

Source: Stem Cell Research and Therapy - February 22, 2019 Category: Stem Cells Authors: Chi Yang, Xiaohan Liu, Kai Zhao, Youming Zhu, Bin Hu, Yong Zhou, Mohan Wang, Yiqun Wu, Chengfei Zhang, Jianguang Xu, Yujie Ning and Duohong Zou Tags: Research Source Type: research