Cancer drug reduces pain, improves symptoms in people with Proteus syndrome

A repurposed cancer drug appears to reduce the severity of lesions and pain experienced by people with Proteus syndrome, a rare genomic disease. Some researchers believe that Joseph Merrick, known as the Elephant Man, may have suffered from Proteus syndrome.
Source: NHGRI Homepage Highlights - Category: Genetics & Stem Cells Source Type: news

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The U.S. Centers for Disease Control and Prevention is investigating a growing number of “severe” lung disease cases that appear to be related to vaping. Since late June, according to the CDC, 94 people in 14 states have come down with serious lung illnesses that may be linked to use of e-cigarettes, which heat substances including nicotine and cannabis to create aerosols that users inhale. The case count has grown high enough to prompt the CDC to work with state health departments to learn more about what could be causing the worrisome conditions, which are primarily affecting adolescents. Although “mor...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized onetime public health Source Type: news
Staying healthy is best done with expert help. We all need medical care at some point. And if chronic illness strikes, it requires the guidance of someone with the ability to make diagnoses and balance treatments that are often aimed at different organ systems. Primary care physicians (PCPs) are generalists who see adult patients for common ailments including respiratory infections, headaches, back pain, and urinary infections. They also manage chronic conditions such as high blood pressure, diabetes, heart disease, obesity, anxiety, and depression. In addition, PCPs have expertise in managing multiple treatments, medicati...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Source Type: blogs
This article presents an approach to assess extraspinal metastases, reviews available interventional techniques in use today, and offers example cases as an introductory primer to the thought process used for selecting the appropriate interventional treatment. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Seminars in Interventional Radiology - Category: Radiology Authors: Tags: Review Article Source Type: research
The purpose of the present study was to examine maternal pain management in children with cancer and the associated factors.
Source: Journal of Pediatric Nursing - Category: Nursing Authors: Source Type: research
This study aims to examine the health-related quality of life in patients with hepatocellular carcinoma.Methods181 patients attending a tertiary center outpatient clinic were interviewed and completed the short form 36 (SF36) questionnaire. The SF36 was used to assess health-related QoL. Cross-sectional analyses by group (age, gender, clinical scores, systemic, and local interventions) as well sequel questionnaires were conducted.ResultsParticipants included were 79% (143/181) men [mean age at first SF36: 63.8 ( ± 12.3; 18.4–85.8) years]. Barcelona Clinic Liver Cancer (BCLC) stadium C was associate...
Source: Journal of Cancer Research and Clinical Oncology - Category: Cancer & Oncology Source Type: research
ConclusionPercutaneous extra-spinal cementopasty is predominantly performed as a stand-alone procedure and for lesions in the bony pelvis. It appears to be an effective tool to manage pain associated with malignant bone tumours. There is however a lack of standardization of the technique among the different publications.
Source: Diagnostic and Interventional Imaging - Category: Radiology Source Type: research
Understanding the magnitude and risk-factors for symptom burden of cancer patients at the end-of-life is critical to guiding effective patient- and system-level interventions.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Tags: Original Article Source Type: research
Authors: Zhang Y, Zhang R, Ding N Abstract Clinical analgesic effect of different doses of nalbuphine combined with remifentanil on postoperative gastric cancer patients was explored. One hundred cases of gastric cancer patients treated from December 2014 to December 2016 in the Xiangyang No. 1 People's Hospital were selected and separated into group A and group B. The dose in group A was 0.2 mg/kg of nalbuphine plus 0.2 µg/kg of remifentanil, and 0.3 mg/kg of nalbuphine plus 0.1 µg/kg of remifentanil in group B. Analgesia was performed by self-controlled intravenous injection. The Visual Analogue Scale...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Clinicians deciding whether to refer a patient or family to specialty palliative care report facing high levels of uncertainty. Most research on medical uncertainty has focused on prognostic uncertainty. As part of a pediatric palliative referral intervention for oncology teams we explored how uncertainty might influence palliative care referrals.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Source Type: research
Breast cancer morbidity and mortality disproportionately affect medically underserved women. Most studies of the experience of living with advanced breast cancer do not focus on this population. A deeper understanding of racial/ethnic minorities ’ and low-income patients’ experiences is needed to reduce breast cancer health and healthcare disparities.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Source Type: research
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