Orbital Neuroblastoma Metastases : DAMS Medicine Unplugged

DAMS Medicine Unplugged is an initiative of DAMS, Leading Medical education academy in India, helping students integrate various aspects of a disease. This is an integrated approach to case of orbital neuroblastoma metastases.Famous Radiology Blog http://www.sumerdoc.blogspot.com TeleRad Providers at www.teleradproviders.com Mail us at sales@teleradproviders.com
Source: Sumer's Radiology Site - Category: Radiology Authors: Source Type: blogs

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Despite intensive multimodal therapy, the survival rate for high risk neuroblastoma (HR-NB) remains
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
CONCLUSIONS: The obtained data indicate that mirtazapine and imipramine have neuroprotective effects against H2O2-induced cell death. Although both antidepressants reduced Bax and p53 mRNA expression, only the protection mediated by imipramine might be due to its ability to enhance Bcl-2/Bax ratio. PMID: 32240535 [PubMed - as supplied by publisher]
Source: Pharmacological Reports - Category: Drugs & Pharmacology Authors: Tags: Pharmacol Rep Source Type: research
In this study, we explored the neuroprotective effects of miR-219a-5p on brain using an in vitro ischemia model (mouse neuroblastoma N2a cells treated with oxyglucose deprivation and reperfusion), and in vivo cerebral I/R model in mice.
Source: Journal of Stroke and Cerebrovascular Diseases - Category: Neurology Authors: Source Type: research
Source: Cancer Management and Research - Category: Cancer & Oncology Tags: Cancer Management and Research Source Type: research
Abstract Alzheimer's disease (AD) has become a major world health problem as the population ages. There is still no available treatment that can stop or reverse the progression of AD. Human amnion epithelial cells (hAECs), an alternative source for stem cells, have shown neuroprotective and neurorestorative potentials when transplanted in vivo. Besides, studies have suggested that stem cell priming with plant-derived bioactive compounds can enhance stem cell proliferation and differentiation and improve the disease-treating capability of stem cells. Verbenalin is an iridoid glucoside found in medicinal herbs of Ve...
Source: Aging - Category: Biomedical Science Authors: Tags: Aging (Albany NY) Source Type: research
This video covers key aspects of neuroblastoma, including the causes, symptoms, diagnosis, and treatment.Osmosis
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Med Students Commentary Source Type: news
We identified 20 survival ‐related long noncoding RNAs (lncRNAs) that might be associated with the spontaneous regression of neuroblastoma (NB) and developed a four‐lncRNA signature risk score. The four‐lncRNA signature is an independent prognostic factor of survival in NB. AbstractBackgroundThe association between long noncoding RNAs (lncRNAs) and spontaneous regression of neuroblastoma (NB) has rarely been investigated and remains unknown.ObjectiveTo identify prognostic lncRNAs involved in the spontaneous regression of NB.MethodsDifferential expression analyses were performed between those samples with an outcome o...
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: ORIGINAL RESEARCH Source Type: research
Chemical Research in ToxicologyDOI: 10.1021/acs.chemrestox.9b00437
Source: Chemical Research in Toxicology - Category: Toxicology Authors: Source Type: research
In this study, 4‐F4t‐NeuroP was introduced into neuroblastoma cells (SH‐SY5Y) and, byin vivo infusion, into rodents. Targeted lipidomic analysis of liver and brain tissues show significant elevation of anti ‐inflammatory hydroxylated‐DHA metabolites and an isomer of neuroprotectin D1, suggesting potential beneficial bioactivities of 4‐F4t‐NeuroP. Additionally, 4‐F4t‐NeuroP treatment in SH‐SY5Y cells and primary neuronal culture consistently upregulates the transcriptional level of the antioxidant enzyme hemeoxygenase‐1, but the effect is reduced when 4‐F4t‐NeuroP is further oxidized. Our data sugg...
Source: FEBS Letters - Category: Biochemistry Authors: Tags: COMMUNICATION Source Type: research
Aerobic glycolysis is a hallmark of metabolic reprogramming that contributes to tumor progression. However, the mechanisms regulating expression of glycolytic genes in neuroblastoma (NB), the most common extra...
Source: Journal of Hematology and Oncology - Category: Hematology Authors: Tags: Research Source Type: research
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