Septin functions during neuro-development, a yeast perspective.

Septin functions during neuro-development, a yeast perspective. Curr Opin Neurobiol. 2019 Feb 18;57:102-109 Authors: Falk J, Boubakar L, Castellani V Abstract Septins, discovered almost half a century ago in yeast, have prominent contributions in a broad range of morphological and functional processes from yeast to human. Septins now emerge as key players of neurodevelopment and more specifically of the mechanisms driving the complex morphological differentiation and compartmentalization of neurons that are fundamental to their function. We review here recent advances in Septin-mediated processes of neuron differentiation, which enlighten similarities and differences between neuron and yeast polarity programs. PMID: 30784977 [PubMed - as supplied by publisher]
Source: Current Opinion in Neurobiology - Category: Neurology Authors: Tags: Curr Opin Neurobiol Source Type: research