Pharmacological Effects on Striatal Resting-State Connectivity in Pediatric Obsessive-Compulsive Disorder: An Opportunity to Modulate Neurodevelopmental Trajectories?

The cortico-striato-thalamo-cortical (CSTC) circuit has been traditionally implicated in the underlying neural pathophysiology of obsessive-compulsive disorder (OCD). The CSTC involves parallel, partly segregated, but intrinsically communicating circuits involved in motor, cognitive, affective, and motivational processes.1,2
Source: Journal of the American Academy of Child and Adolescent Psychiatry - Category: Psychiatry Authors: Tags: Editorial Source Type: research