Periodontal Disease in Pregnancy: The Influence of General Factors and Inflammatory Mediators

Gil, Luc ía / Mínguez, Ignacio / Caffesse, Raul / Llambés, FernandoPage 69 - 73Purpose: To determine the influence of plaque and progesterone on periodontitis in pregnant women and their relationship with inflammatory mediators.Materials and Methods: A longitudinal observational study of 60 pregnant women was undertaken in two observation periods. During the third trimester, plaque Index (PI), bleeding on probing (BOP), probing pocket depth (PPD), and clinical attachment level (CAL) were assessed, and the basal levels of progesterone, CRP, IL-6 and TNF- α in plasma were measured. The second observation phase was carried out 6 weeks after childbirth, when periodontal indices, progesterone and serum levels of CRP were again evaluated.Results: Periodontal disease was moderate in 18.3%. PI and toothbrushing proved to have a correlation with the severity of periodontitis. High levels of CRP were significantly correlated (p
Source: Oral health and Preventive dentistry - Category: Dentistry Source Type: research