Identification of antiplasmodial triterpenes from Keetia species using NMR-based metabolic profiling

ConclusionNMR-based metabolomics combined with supervised multivariate data analysis is a powerful strategy for the identification of bioactive metabolites in plant extracts. Moreover, combination of statistical total correlation spectroscopy with 2D NMR allowed a detailed analysis of different triterpenes, overcoming the challenge posed by their structure similarity and coalescence in the aliphatic region.
Source: Metabolomics - Category: Biology Source Type: research