Combining Strengths for Multi-genome Visual Analytics Comparison.

Combining Strengths for Multi-genome Visual Analytics Comparison. Bioinform Biol Insights. 2019;13:1177932218825127 Authors: Diaz-Del-Pino S, Rodriguez-Brazzarola P, Perez-Wohlfeil E, Trelles O Abstract The eclosion of data acquisition technologies has shifted the bottleneck in molecular biology research from data acquisition to data analysis. Such is the case in Comparative Genomics, where sequence analysis has transitioned from genes to genomes of several orders of magnitude larger. This fact has revealed the need to adapt software to work with huge experiments efficiently and to incorporate new data-analysis strategies to manage results from such studies. In previous works, we presented GECKO, a software to compare large sequences; now we address the representation, browsing, data exploration, and post-processing of the massive amount of information derived from such comparisons. GECKO-MGV is a web-based application organized as client-server architecture. It is aimed at visual analysis of the results from both pairwise and multiple sequences comparison studies combining a set of common commands for image exploration with improved state-of-the-art solutions. In addition, GECKO-MGV integrates different visualization analysis tools while exploiting the concept of layers to display multiple genome comparison datasets. Moreover, the software is endowed with capabilities for contacting external-proprietary and third-party services for ...
Source: Bioinformatics and Biology Insights - Category: Bioinformatics Authors: Tags: Bioinform Biol Insights Source Type: research