PIVOTAL trial: iron loading improves clinical outcomes

PIVOTAL trial: iron loading improves clinical outcomesPIVOTAL trial: iron loading improves clinical outcomes, Published online: 21 February 2019; doi:10.1038/s41581-019-0128-5The PIVOTAL trial shows that proactive intravenous (i.v.) iron administration reduces cardiovascular events and deaths, transfusions and erythropoiesis-stimulating agent doses and does not increase infections in patients on haemodialysis. These findings upend the warnings of guidelines and experts about the dangers of i.v. iron and prove that maintaining low iron stores is harmful.

Source: Nature Reviews Nephrology - February 21, 2019 Category: Urology & Nephrology Authors: Daniel W. Coyne Source Type: research