Patient characteristics and neuroimaging for headache in the ED

Cain MR, Arkilo D, Linabery AM, Kharbanda AB. Emergency Department Use of Neuroimaging in Children and Adolescents Presenting with Headache. J Pediatr 2018;201:196-201.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Current Best Evidence Source Type: research

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Publication date: Available online 16 August 2019Source: The LancetAuthor(s): Michel D Ferrari, Hans Christoph Diener, Xiaoping Ning, Maja Galic, Joshua M Cohen, Ronghua Yang, Matthias Mueller, Andrew H Ahn, Yael Carmeli Schwartz, Melissa Grozinski-Wolff, Lindsay Janka, Messoud AshinaSummaryBackgroundAntibodies targeting calcitonin gene-related peptide (CGRP) or its receptor have shown efficacy in the prevention of migraine attacks. We investigated the efficacy and tolerability of fremanezumab, a fully humanised CGRP antibody, in patients with migraine who had previously not responded to two to four classes of migraine pre...
Source: The Lancet - Category: General Medicine Source Type: research
Publication date: Available online 16 August 2019Source: The LancetAuthor(s): Alessandro Tessitore, Antonio Russo
Source: The Lancet - Category: General Medicine Source Type: research
In this report, considering also the literature information, a case of G.sanguinis which is thought to cause meningitis was presented. Our case is a 39-year-old female patient with a lumboperitoneal shunt. The patient was admitted to the neurosurgery clinic with a headache and vision loss and was hospitalized in the service with a pre-diagnosis of pseudotumor cerebri. Neurological examination revealed no pathological findings. Eye examination revealed mild papillary edema, local retinal hemorrhage, and bilateral expansion in retinal vascularization. There was no pathologic findings in the brain magnetic resonance imaging. ...
Source: Mikrobiyoloji Bulteni - Category: Microbiology Tags: Mikrobiyol Bul Source Type: research
ConclusionsUtilities estimated from the general population sample may be used to represent route of administration and AEs in cost-utility models. Results from the patient sample indicate that these treatment characteristics have an impact on patient preference.
Source: Quality of Life Research - Category: Health Management Source Type: research
Our technical consulting group at Nelson Laboratories acts as a bridge between medical device companies and regulatory bodies, putting us in a good position to understand both sides and what they need from each other. This also creates an opportunity for us to recognize the typical deficiencies, mishaps, or errors that are identified by regulatory agencies during the submission process and to provide our expertise to medical device manufacturers about how to structure and document their submission paperwork to avoid some of these common mistakes. Oftentimes we receive feedback from FDA or a notified body that a submission ...
Source: MDDI - Category: Medical Devices Authors: Tags: Regulatory and Compliance Source Type: news
The bacteria, from the genus pseudomonas and the genus burkholderia, can enter the bloodstream and cause serious, life-threatening infections.
Source: WebMD Health - Category: Consumer Health News Source Type: news
Scientists from the Don Carlo Gnocchi Foundation in Milan tested the diet on migraine sufferers. It is loved by Hollywood's resident 'health guru' Gwyneth Paltrow and Bond girl Halle Berry.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Pfizer has recalled two lots of migraine drug Relpax after finding those lots “may not meet Pfizer’s in-house microbiological specification for the potential presence” of two kinds of bacteria.
Source: PharmaManufacturing.com - Category: Pharmaceuticals Source Type: news
ConclusionsNusinersen demonstrated a favorable safety profile in children with symptomatic infantile- and later-onset SMA. Most reported AEs and serious AEs were consistent with the nature and frequency of events typically seen with SMA or in the context of lumbar puncture procedures.RegistrationNCT01494701, NCT01703988, NCT01839656, NCT02193074, NCT02292537, NCT01780246, NCT02052791.
Source: CNS Drugs - Category: Neurology Source Type: research
ConclusionSymptoms of eighth nerve dysfunction are present in over half of patients with GCA. Recovery with steroids was predicted by concurrence with headache in terms of both timing and location. It appears that eighth nerve involvement, especially acute hearing loss, is a not infrequent feature of GCA and often responds well to steroid therapy. Clinicians should enquire about these symptoms when evaluating a patient for possible GCA.Key Points• Deafness is a frequent presenting feature of giant cell arteritis.• Vertigo, tinnitus and loss of balance are also often reported by GCA sufferers.• Steroid therap...
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
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