Prevalence and factors associated with gastroesophageal reflux disease in southern India: A community-based study

ConclusionSymptomatic GERD was found in 8.2% of respondents in this representative southern Indian community, being more prevalent in urban residents, women, older, and obese individuals.
Source: Indian Journal of Gastroenterology - Category: Gastroenterology Source Type: research

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Publication date: Available online 18 November 2019Source: PeptidesAuthor(s): Rabeet Khan, Alejandra Tomas, Guy A. RutterAbstractGlucose-dependent insulinotropic polypeptide (GIP) is a gut-derived incretin that, in common with glucagon-like peptide-1 (GLP-1), has both insulin releasing and extra-pancreatic glucoregulatory actions. GIP is released in response to glucose or fat absorption and acts on the GIP receptor (GIPR) to potentiate insulin release from pancreatic beta cells. GIP has also been shown to promote beta cell survival and stimulate the release of GLP-1 from islet alpha cells. There is now evidence to suggest ...
Source: Peptides - Category: Biochemistry Source Type: research
Abstract The detrimental effect of (NO2-) on environment, a sensitive and selective detection of nitrite (NO2-) ions with point-to-care device is need to be fabricated. Herein, we report the non-enzymatic nitrite sensor using a novel reduced graphene oxide/molybdenum disulfide/poly (3, 4-ethylene dioxythiophene) (rGO/MoS2/PEDOT) nanocomposite electrode. The rGO/MoS2/PEDOT nanocomposite was synthesized using facile and cost-effective hydrothermal and polymerization approaches. The characteristics of rGO-MoS2-PEDOT nanocomposite was investigated by X-ray diffraction (XRD), Fourier transform infrared (FT-IR), Raman, ...
Source: Analytica Chimica Acta - Category: Chemistry Authors: Tags: Anal Chim Acta Source Type: research
A previously healthy, well-appearing 42-year-old female living in a modern, high-rise apartment in downtown Los Angeles calls 9-1-1 at 5:30 am complaining of worsening of a burning, epigastric pain she had been experiencing for the last three days. She reports associated nausea and non-bloody, non-bilious vomiting, and that she couldn’t manage to get comfortable in bed until she finally decided to call for help at daybreak. During her 9-1-1 call, she reports “pain, like heartburn, that just woke me up again and I had to throw up, … and then I was sweating so much.” Using the Los Angeles Tiered Disp...
Source: JEMS Special Topics - Category: Emergency Medicine Authors: Tags: Exclusive Articles Cardiac & Resuscitation Source Type: news
Publication date: October 2017Source: Best Practice &Research Clinical Gastroenterology, Volume 31, Issue 5Author(s): Eivind Ness-Jensen, Jesper LagergrenAbstractGastro-oesophageal reflux disease (GORD) develops when reflux of gastric content causes troublesome symptoms or complications. The main symptoms are heartburn and acid regurgitation and complications include oesophagitis, strictures, Barrett's oesophagus and oesophageal adenocarcinoma. In addition to hereditary influence, GORD is associated with lifestyle factors, mainly obesity. Tobacco smoking is regarded as an aetiological factor of GORD, while alcohol cons...
Source: Best Practice and Research Clinical Gastroenterology - Category: Gastroenterology Source Type: research
Conclusion PPIs are commonly used medicines for acid reflux. This may seem like alarming news for the many people in the UK who take them, but it's important to remember that the overall risk of stomach cancer is still very low. This study has several limitations that mean we should be cautious about the results: This type of study can't prove PPIs caused the increased risk of cancer. The increased risk could be down to other factors. Researchers were unable to adjust their figures to take account of some relevant confounding factors, such as alcohol and tobacco use, as these weren't routinely recorded. Almost all the pati...
Source: NHS News Feed - Category: Consumer Health News Tags: Cancer Source Type: news
Publication date: Available online 7 September 2017 Source:Best Practice & Research Clinical Gastroenterology Author(s): Eivind Ness-Jensen, Jesper Lagergren Gastro-oesophageal reflux disease (GORD) develops when reflux of gastric content causes troublesome symptoms or complications. The main symptoms are heartburn and acid regurgitation and complications include oesophagitis, strictures, Barrett's oesophagus and oesophageal adenocarcinoma. In addition to hereditary influence, GORD is associated with lifestyle factors, mainly obesity. Tobacco smoking is regarded as an aetiological factor of GORD, while alcohol consump...
Source: Best Practice and Research Clinical Gastroenterology - Category: Gastroenterology Source Type: research
Conclusion This prospective cohort study aimed to see whether a test performed on patients with non-cancerous Barrett's oesophagus may be able to predict whether the condition progressed to oesophageal cancer.  Overall, they found genetic diversity in the oesophageal cell samples at the start of the study seemed to be linked to the risk of cancer progression. However, the research has limitations to consider: By design, this study is only able to draw links – it does not propose treatment or lifestyle steps to be taken to reduce risk. The sample of patients in this study is small, so we...
Source: NHS News Feed - Category: Consumer Health News Tags: Cancer Genetics/stem cells Source Type: news
Director chair, film slate and load horn. Here’s a proposal for you: If, by following the Wheat Belly lifestyle, a long list of conditions are reduced or reversed at no risk, almost no cost, reversing even chronic and potentially fatal conditions . . . does that mean that the notion of self-directed health might be on the horizon, i.e., putting control over health back in our own hands? I think it does. No, we will never implant our own defibrillators or take out our own gallbladders. But so many chronic health conditions afflicting modern humans recede that I believe that it is entirely reasonable to start talking a...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Wheat Belly Lifestyle arthritis autoimmune diabetes eating disorder gluten grains Inflammation joint Weight Loss Source Type: blogs
It’s 9:30 on a typical weekday night. Maybe you’ve just rolled in from work, or maybe a workout (damn you). Maybe you’re already sprawled out on the couch, remote in-hand, Netflix streaming. Suddenly it hits you — you haven’t eaten since lunch, and you’re starving. You reach into the freezer, grab a frozen pizza or a leftover slice and chow down. Bad idea. You've just created the perfect environment for disrupted sleep, owing to our stomach's skilled ability to pump out acid at the first sign of food. Fact is, whether we’re home or out to dinner, plenty of us end up eating lat...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
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