A Review on the Effect of Tumor Necrosis Factor Inhibitors on Structural Progression in Early Axial Spondyloarthritis Using Magnetic Resonance Imaging

ConclusionsIn conclusion, treatment with TNF α inhibitors reduces MRI-evident inflammatory lesions in the SIJ and spine of patients with early axSpA for up to 4 years. There is less evidence of benefits on structural lesions. Additional studies are required to determine whether TNFα-inhibitor therapy can limit or delay radiological progress ion in patients with early axSpA.FundingPfizer.

http://link.springer.com/10.1007/s40744-019-0141-y

Source: Rheumatology and Therapy - February 20, 2019 Category: Rheumatology Source Type: research