Multiple Cerebral Hemorrhagic Lesions Depicted by Susceptibility-Weighted Imaging in a Patient with Down Syndrome: Case Report

Our objective is to study a 53-year-old woman with Down syndrome presented with massive lobar hematoma in the left fronto-parietal lobe, and who underwent craniotomy and hematoma evacuation. Histopathological diagnosis of surgical specimen was amyloid angiopathy. Postoperative magnetic resonance studies were performed. The lesion this time showed mixed intensity on susceptibility-weighted imaging. In addition, multiple hypointense lesions were evident. An old previously unidentified hemorrhage in the right temporo-parietal lobe was accompanied by superficial cortical siderosis.
Source: Journal of Stroke and Cerebrovascular Diseases - Category: Neurology Authors: Tags: Case Report Source Type: research

Related Links:

.
Source: Social Work in Health Care - Category: International Medicine & Public Health Authors: Source Type: research
In conclusion, in the present study we attempted to investigate the existence of the SFOF using an anatomical and functional approach. According to our results, the SFOF may not exist in the human brain.
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Publication date: Available online 21 January 2020Source: SeizureAuthor(s): Petra Redfors, Lukas Holmegaard, Annie Pedersen, Christina Jern, Kristina MalmgrenAbstractPurposeTo assess long-term incidence and predictors of post-stroke epilepsy (PSE) and to evaluate the antiepileptic drug (AED) treatment in a well characterized cohort of middle-aged patients.MethodsThe study is based on the Sahlgrenska Study on Ischemic stroke, and included 1066 adult patients with first-ever or recurrent acute ischemic stroke (AIS) before the age of 70. Early seizures (ES) were defined as seizures within one week and PSE as unprovoked seizur...
Source: Seizure - Category: Neurology Source Type: research
The federal government is taking Ohio's side in a lawsuit over the state law prohibiting doctors from performing abortions based on a fetal diagnosis of Down syndrome
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
Condition:   Stroke (CVA) or TIA Interventions:   Drug: Angong Niuhuang Wan;   Drug: Angong Niuhuang Wan Placebo Sponsor:   Chinese University of Hong Kong Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Ischemic Stroke;   Cognitive Impairment;   Outcome, Fatal Intervention:   Diagnostic Test: Montreal Cognitive Assessment (MoCA) Sponsor:   Mansoura University Hospital Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSION: The prevalence of carotid plaque was very high in the high-risk stroke population in southwestern China. Variants in genes involved in the endothelial function and inflammation were associated with the carotid plaque. The high-risk interactive genotype among rs7923349, rs1991013, rs1609682, and rs8081248 was independently associated with a higher risk of vulnerable plaque. PMID: 31956237 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - Category: Cardiology Tags: J Atheroscler Thromb Source Type: research
CONCLUSION: Many diseases can be associated with Moya-Moya syndrome. Symptomatic patients should undergo surgery, but the risk of postoperative complications appears to be greater than that encountered in patients with non-syndromic Moya-Moya angiopathy. PMID: 29475609 [PubMed - as supplied by publisher]
Source: Neuro-Chirurgie - Category: Neurosurgery Authors: Tags: Neurochirurgie Source Type: research
Purpose of review: Alzheimer's disease is most likely universal in older individuals with Down syndrome, due to having three copies of the amyloid precursor protein gene, resulting in amyloid-beta plaque deposition. Down syndrome is an important population in which to consider clinical trials of treatments to prevent or delay the development of dementia. However, assessment of subtler cognitive changes is challenging due to the presence of intellectual disability. Recent findings: Recent research confirmed that older adults with Down syndrome often present with cognitive decline: more than 80% may experience dementia by a...
Source: Current Opinion in Psychiatry - Category: Psychiatry Tags: NEURODEVELOPMENTAL DISORDERS: Edited by James C. Harris Source Type: research
Abstract PURPOSE OF REVIEW: Alzheimer's disease is most likely universal in older individuals with Down syndrome, due to having three copies of the amyloid precursor protein gene, resulting in amyloid-beta plaque deposition. Down syndrome is an important population in which to consider clinical trials of treatments to prevent or delay the development of dementia. However, assessment of subtler cognitive changes is challenging due to the presence of intellectual disability. RECENT FINDINGS: Recent research confirmed that older adults with Down syndrome often present with cognitive decline: more than 80% may ex...
Source: Epilepsy Curr - Category: Neurology Authors: Tags: Curr Opin Psychiatry Source Type: research
More News: Craniotomy | Down's Syndrome | Hemorrhagic Stroke | Stroke | Study