Host Specificity Of Avian Metapneumoviruses.

Host Specificity Of Avian Metapneumoviruses. Avian Pathol. 2019 Feb 19;:1-19 Authors: Brown PA, Allée C, Courtillon C, Szerman N, Lemaitre E, Toquin D, Mangart JM, Amelot M, Eterradossi N Abstract To date four subgroups of avian metapneumoviruses have been defined (AMPV-A, B, C and D) based on genetic and antigenic differences. The extent of infection in the three principal species (turkeys, chickens and ducks) by these subgroups however, is not well defined. Here, a series of controlled and ethically-approved experimental infections were performed in SPF turkeys, chickens and ducks with each of the four AMPV subgroups. For subgroup C, one strain isolated from turkeys in the USA (turkey AMPV-C) and one isolated from ducks in France (duck AMPV-C) were compared. Globally these extensive experimental trials demonstrated that AMPV-A, B, Turkey C and D were well adapted to Galliformes, especially turkeys, however chickens showed limited clinical signs and differences in seroconversion and transmission. Notably chickens did not transmit AMPV-A to contacts and were shown for the first time to be susceptible to AMPV-D. The duck AMPV-C was well adapted to ducks, however chickens and turkeys seroconverted and were positive by virus isolation. In addition, seroconversion of contact turkeys to duck AMPV-C demonstrated horizontal transmission of this virus in a non-Palmiped species under our experimental conditions. Interestingly in chickens and turkeys, duck ...
Source: Avian Pathology - Category: Pathology Authors: Tags: Avian Pathol Source Type: research

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