Severe Migraine Associated with Nickel allergy requiring surgical removal of atrial septal device

We report a 16 years-old male who required surgical explantation of the device 6 years after closure because of debilitating headaches. He had grade I reaction to nickel following skin testing. Intraoperatively, the device had not fully endothelialised. Immediately after surgery, his headaches completely resolved. Long-term Nickel allergy may cause severe migraine, secondary to lack of endothelialisation of a device. Extreme cases may require surgical removal of the device.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research