Viruses, Vol. 11, Pages 173: Targeting the Viral Polymerase of Diarrhea-Causing Viruses as a Strategy to Develop a Single Broad-Spectrum Antiviral Therapy

We describe the functional and structural similarities of the different viral polymerases, the antiviral effect of reported polymerase inhibitors and highlight common features that might be exploited in an attempt of designing such pan-polymerase inhibitor.

Source: Viruses - February 20, 2019 Category: Virology Authors: Marcella Bassetto Jana Van Dycke Johan Neyts Andrea Brancale Joana Rocha-Pereira Tags: Review Source Type: research