Computer-aided confocal laser endomicroscopy in inflammatory bowel disease: probing deeper into what it means

Confocal laser endomicroscopy (CLE) is an endoscopic tool that enables micron-level spatial resolution and imaging of the GI mucosa during endoscopy.1 Given the potential for in  vivo assessment, this technology has the potential to improve our real-time assessment of mucosa-based disease during endoscopy.2-4 One area with emerging data regarding the use of CLE for disease-specific assessment is inflammatory bowel disease (IBD). Various studies have examined whether CLE ca n detect mucosal changes related to inflammation, and they have described features of inflamed mucosa such as irregular or tortuous crypts, wider lumens, and fluorescein leakage to the interstitial space.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: New methods Source Type: research