Variations in glucose /C-peptide ratio in patients with type 2 diabetes associated with renal function

Accurate dosing of medications for glycemic control is a challenge for clinicians in diabetic patients with kidney disease. Diminishing glomerular filtration rates are associated with decreased renal clearance of insulin and increased prevalence of hypoglycemic episodes. Measurement of glucose /C peptide ratios may be useful to guide dosing in those patients who receive powerful insulin secretogogues as glomerular function decreases with age and disease.
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Source Type: research