Safety of rapid switching from amiodarone to dofetilide in atrial fibrillation patients with an implantable cardioverter –defibrillator

Dofetilide is a class III antiarrhythmic drug commonly used for treatment of atrial fibrillation. Drug guidelines mandate a 3-month waiting period before initiating dofetilide after  amiodarone use. Whether patients with an implantable cardioverter–defibrillator (ICD) can be rapidly switched from amiodarone to dofetilide is not known.

Source: Heart Rhythm - January 30, 2019 Category: Cardiology Authors: Sharan Prakash Sharma, Mohit Turagam, Donita Atkins, Sudha Bommana, Courtney Jeffrey, Diana Newton, Cheri Nydegger, Heidi Carroll, Rakesh Gopinathannair, Andrea Natale, Dhanunjaya Lakkireddy Source Type: research