M-BLANK: a program for the fitting of X-ray fluorescence spectra

The X-ray fluorescence data from X-ray microprobe and nanoprobe measurements must be fitted to obtain reliable elemental maps. The most common approach in many fitting programs is to initially remove a per-pixel baseline. Using X-ray fluorescence data of yeast and glial cells, it is shown that per-pixel baselines can result in significant, systematic errors in quantitation and that significantly improved data can be obtained by calculating an average blank spectrum and subtracting this from each pixel.

Source: Journal of Synchrotron Radiation - February 19, 2019 Category: Physics Authors: Crawford, A.M. Deb, A. Penner-Hahn, J.E. Tags: X-ray fluorescence per-pixel baselines X-ray microprobes elemental maps X-ray nanoprobes research papers Source Type: research