Comparative 3D genome organization in apicomplexan parasites [Microbiology]

The positioning of chromosomes in the nucleus of a eukaryotic cell is highly organized and has a complex and dynamic relationship with gene expression. In the human malaria parasite Plasmodium falciparum, the clustering of a family of virulence genes correlates with their coordinated silencing and has a strong influence on...

Source: Proceedings of the National Academy of Sciences - February 19, 2019 Category: Science Authors: Evelien M. Bunnik, Aarthi Venkat, Jianlin Shao, Kathryn E. McGovern, Gayani Batugedara, Danielle Worth, Jacques Prudhomme, Stacey A. Lapp, Chiara Andolina, Leila S. Ross, Lauren Lawres, Declan Brady, Photini Sinnis, Francois Nosten, David A. Fidock, Emma Tags: PNAS Plus Source Type: research