Energy ‐Converting Nanomedicine

This comprehensive review summarizes the recent advances in engineering versatile nanotherapeutics for energy ‐converting nanomedicine enabled by external energy input, including photo‐based, radiation‐based, ultrasound‐based, magnetic field‐based, microwave‐based, electric field‐based, and radiofrequency‐based nanomedicines. AbstractSerious side effects to surrounding normal tissues and unsatisfactory therapeutic efficacy hamper the further clinic applications of conventional cancer ‐therapeutic strategies, such as chemotherapy and surgery. The fast development of nanotechnology provides unprecedented superiorities for cancer therapeutics. Externally activatable therapeutic modalities mediated by nanomaterials, relying on highly effective energy transformation to release ther apeutic elements/effects (cytotoxic reactive oxygen species, thermal effect, photoelectric effect, Compton effect, cavitation effect, mechanical effect or chemotherapeutic drug) for cancer therapies, categorized and termed as “energy‐converting nanomedicine,” have arouse considerable concern d ue to their noninvasiveness, desirable tissue‐penetration depth, and accurate modulation of therapeutic dose. This review summarizes the recent advances in the engineering of intelligent functional nanotherapeutics for energy‐converting nanomedicine, including photo‐based, radiation‐based, u ltrasound‐based, magnetic field‐based, microwave‐based, electric field‐based, and ra...
Source: Small - Category: Nanotechnology Authors: Tags: Review Source Type: research