Single nucleotide polymorphisms in MAP3K1, FGF10 and FGFR2 genes as breast cancer predictors

Introduction: Breast cancer (BC) is a heterogeneous disease caused by combination of several genetic, epigenetic and environmental factors. At about hundred single nucleotide polymorphisms significantly associate with the BC. Some of them are highly penetrant such as BRCA1 and BRCA2, but majority of them less penetrant.

Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 19, 2019 Category: OBGYN Authors: Pavol Zubor, Alexandra Gondova, Zuzana Dankova, Marian Grendar, Tibor Bielik, Zuzana Laucekova, Marek Samec, Katarina Zelinova, Mariana Jagelkova, Jan Danko Tags: Session 30 – Oncology: Breast Source Type: research