Placental transfer of elvitegravir and cobicistat in an ex vivo human cotyledon double perfusion model

Introduction: Sustained suppression of plasma viral load is the key to preventing vertical transmission from HIV-infected women to their infants. Current guidelines recommend antiretroviral therapy for all HIV infected pregnant women, starting before the pregnancy. However, the choice of which antiretroviral medications to be used must take into account the tolerance for the developing fetus, in view of the placental transfer of the drugs used.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Session 16 – Obstetrics: High risk pregnancy Source Type: research