Tumor cell detection in the bone marrow of DCIS patients is not associated with routine clinicopathological features

Introduction: In invasive breast cancer, the detection of disseminated tumor cells (DTCs) in the bone marrow (BM) is associated with larger tumor size, axillary lymph node involvement, estrogen (ER) and progesterone (PR) receptor negativity and human epidermal growth factor receptor 2 (HER2) positivity as well as aggressive molecular subtype (non-luminal). In patients with ductal carcinoma in situ (DCIS) any such association has yet to be shown.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Session 30 – Oncology: Breast Source Type: research