Influence of CYP2C19 Metabolizer Status on Escitalopram/Citalopram Tolerability and Response in Youth With Anxiety and Depressive Disorders

Stacey L. Aldrich, Ethan A. Poweleit, Cynthia A. Prows, Lisa J. Martin, Jeffrey R. Strawn, Laura B. Ramsey
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research

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Authors: Łabuz-Roszak B, Niewiadomska E, Kubicka-Bączyk K, Skrzypek M, Tyrpień-Golder K, Majewska A, Matejczyk A, Dobrakowski P, Pierzchała K Abstract OBJECTIVES: Pain is one of the most frequently reported symptoms of multiple sclerosis (MS). It affects the daily functioning of patients, limits the ability to work and reduces the joy of life. The aim of the study was to analyze the impact of pain on quality of life as well as symptoms of anxiety and depression in patients with MS. METHODS: The study included 144 patients with diagnosed MS (mean age 41±12 years, mean illness duration 10.3±8.6 ...
Source: Psychiatria Polska - Category: Psychiatry Tags: Psychiatr Pol Source Type: research
Authors: Herman A Abstract In recent years increased interest in the connection of intestinal microflora and the state of human health resulted in a great deal of research on the influence of intestinal microflora in particular on mental health, including works on affective functions of the central nervous system (CNS). Previous studies on animals have revealed the existence of a bi-directional communication system between the gastrointestinal microbiota and the central nervous system, the so-called .gut-brain axis' which modulates functioning of CNS through immunological, endocrine and neuronal mechanisms. Clinica...
Source: Psychiatria Polska - Category: Psychiatry Tags: Psychiatr Pol Source Type: research
This article presents recommendations of the Polish Psychiatric Association regarding approach to pregnancy loss and unsuccessful in vitro treatment of infertility. From the psychological perspective pregnancy loss and perinatal death are amongst the most stressful events in human life - carrying increased risk of developing affective, anxiety or post-traumatic stress disorders. Psychologists, physicians and the rest of the medical staff should provide integrated and individualized care which should be based on respect, empathy and expertise. The necessary phases of support for women experiencing pregnancy loss are: (1) ph...
Source: Psychiatria Polska - Category: Psychiatry Tags: Psychiatr Pol Source Type: research
Conclusions: Bipolar disorder is common among primary care patients presenting with depression; it is often treated exclusively in primary care. Clinicians should be alert for symptoms of bipolar disorder in undiagnosed patients, know what symptoms probabilistically suggest bipolar versus unipolar depression, have expertise in providing ongoing treatment to diagnosed patients, and be knowledgeable about managing common medication-related side effects and comorbidities. Prompt and accurate diagnosis is critical. PMID: 31311335 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
Publication date: 1 December 2019Source: Personality and Individual Differences, Volume 151Author(s): Amy B. Brunell, Melissa T. BuelowAbstractWe sought to examine the extent to which people are honest when reporting their psychological well-being and their levels of narcissism. We also sought to examine narcissists' psychological well-being, such as their levels of anxiety and depression. We used a bogus pipeline paradigm to examine these questions. Participants were randomly assigned to one of three study conditions: a bogus pipeline condition wherein they were led to believe they were connected to a polygraph, an anonym...
Source: Personality and Individual Differences - Category: Psychiatry & Psychology Source Type: research
This study used bibliometric analysis method to present the number of published studies and the categories distribution, and analyze 42 high-frequency keywords based on 1288 papers from the Web of Science database from 1964 to 2018. The results were as follows. (1) Research had proceeded through a rising stage, falling stage, and bottleneck stage, which involved the categories of psychology, medicine, and management. (2) Research evolved from physical health issues, such as diseases, to psychological health issues such as anxiety, depression, and organizational management issues, such as occupational stress. (3) High-frequ...
Source: Personality and Individual Differences - Category: Psychiatry & Psychology Source Type: research
The myth was created by drug companies to sell serotonin reuptake inhibiting (SSRI) drugs. → Support PsyBlog for just $4 per month. Enables access to articles marked (M) and removes ads. → Explore PsyBlog's ebooks, all written by Dr Jeremy Dean: Accept Yourself: How to feel a profound sense of warmth and self-compassion The Anxiety Plan: 42 Strategies For Worry, Phobias, OCD and Panic Spark: 17 Steps That Will Boost Your Motivation For Anything Activate: How To Find Joy Again By Changing What You Do
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Antidepressants subscribers-only Source Type: blogs
The objective of this study was to analyze changes in prefrontal cortex (PFC) activity in response to visual exposure to affective faces, and to ascertain whether changes in PFC activity were related to scores in neuroticism, including depression, anxiety, low self-esteem and dependence facets. Fifty-two healthy undergraduate female students participated in the present study. Results showed significant differences depending on face valence in the left and right ventrolateral PFC. We found a reduction in oxygen consumption in reaction to neutral and happy faces, and a small increase in oxygenation in reaction to angry faces...
Source: Neuropsychologia - Category: Neurology Source Type: research
Authors: Plitzko L, Mehnert-Theuerkauf A, Götze H Abstract INTRODUCTION: Resilience is considered as a resource in coping with psychological distress and traumatic experiences and plays an increasing role in psycho-oncology research. The aim of the study is to analyse the resilience in long-term cancer survivors depending on depression, anxiety, sociodemographic and disease-related factors and to compare with the general population. MATERIAL AND METHODS: Our study includes data from 972 patients (53% male, mean age=67 years, 25% prostate cancer, 22% breast cancer) 5 or 10 years after cancer diagnosis via t...
Source: PPmP Psychotherapie Psychosomatik Medizinische Psychologie - Category: Psychiatry & Psychology Tags: Psychother Psychosom Med Psychol Source Type: research
We present a care model that is based on a telemental treatment approach for depression and anxiety disorders. Central is the piloting of psychotherapeutic video consultations in the general practice. The following article provides an overview of the care model and provides results concerning the intent to adopt the model in office-based psychotherapists. PMID: 31315140 [PubMed - as supplied by publisher]
Source: PPmP Psychotherapie Psychosomatik Medizinische Psychologie - Category: Psychiatry & Psychology Tags: Psychother Psychosom Med Psychol Source Type: research
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