Transgender Hormone Therapy Could Pose Heart Dangers

MONDAY, Feb. 18, 2019 -- Men and women who get hormone therapy during gender transition treatment may face a much higher risk for developing heart disease, new Dutch research cautions. " In light of our results, we urge both physicians and...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news

Related Links:

FRIDAY, June 14, 2019 (American Heart Association News) -- The impact of hormone therapy on the heart health of transgender men and women has been the subject of several studies published within the last year. But medical experts and researchers...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Maunil K. Desai1 and Roberta Diaz Brinton2,3* 1School of Pharmacy, University of Southern California, Los Angeles, CA, United States 2Center for Innovation in Brain Science, University of Arizona, Tucson, AZ, United States 3Departments of Pharmacology and Neurology, College of Medicine, University of Arizona, Tucson, AZ, United States Women have a higher incidence and prevalence of autoimmune diseases than men, and 85% or more patients of multiple autoimmune diseases are female. Women undergo sweeping endocrinological changes at least twice during their lifetime, puberty and menopause, with many women undergoin...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Conclusions: These data suggest that higher FSH in postmenopausal women is related to higher levels of both TC and LDL-C.
Source: Menopause - Category: OBGYN Tags: Original Articles Source Type: research
CONCLUSIONS: Patient-reported pretreatment sexual function and comorbidities enables stratification and prediction of erectile function. EPIC subset questions with baseline comorbidities may potentially serve as a quick and practical clinical tool for predicting sexual survivorship. PMID: 31005217 [PubMed - in process]
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - Category: Radiology Authors: Tags: Radiother Oncol Source Type: research
This study demonstrated that the incidence of ischemic heart disease and death were three times higher among men with low birth weight compared to men with high birth weight (5). Epidemiological investigations of adults born at the time of the Dutch famine between 1944 and 1945 revealed an association between maternal starvation and a low infant birth weight with a high incidence of hypertension and coronary heart disease in these adults (23). Furthermore, Painter et al. reported the incidence of early onset coronary heart disease among persons conceived during the Dutch famine (24). In that regard, Barker's findin...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Publication date: Available online 26 February 2019Source: The Journal of Steroid Biochemistry and Molecular BiologyAuthor(s): Francesca Fortini, Francesco Vieceli Dalla Sega, Cristiana Caliceti, Elisabetta Lambertini, Antonio Pannuti, Daniel S. Peiffer, Cristina Balla, Paola RizzoAbstractEstrogen regulates a plethora of biological processes, under physiological and pathological conditions, by affecting key pathways involved in the regulation of cell proliferation, fate, survival and metabolism. The Notch receptors are mediators of communication between adjacent cells and are key determinants of cell fate during developmen...
Source: The Journal of Steroid Biochemistry and Molecular Biology - Category: Biochemistry Source Type: research
Publication date: Available online 26 November 2018Source: European UrologyAuthor(s): Kerri Beckmann, Hans Garmo, Jan Adolfsson, Cecilia Bosco, Eva Johansson, David Robinson, Lars Holmberg, Par Stattin, Mieke Van HemelrijckAbstractBackgroundSome studies suggest that gonadotropin-releasing hormone (GnRH) agonists are associated with higher risk of adverse events than antiandrogens (AAs) monotherapy. However, it has been unclear whether this is due to indication bias.ObjectiveTo investigate rates of change in comorbidity for men on GnRH agonists versus AA monotherapy in a population-based register study.Design, setting, and ...
Source: European Urology - Category: Urology & Nephrology Source Type: research
This study prospectively examined physical activity levels and the incidence of heart failure (HF) in 137,303 women, ages 50 to 79 years, and examined a subset of 35,272 women who, it was determined, had HF with preserved ejection fraction (HFpEF) and HF with reduced EF (HFrEF).BackgroundThe role of physical activity in HF risk among older women is unclear, particularly for incidence of HFpEF or HFrEF.MethodsWomen were free of HF and reported ability to walk at least 1 block without assistance at baseline. Recreational physical activity was self-reported. The study documented 2,523 cases of total HF, and 451 and 734 cases ...
Source: JACC: Heart Failure - Category: Cardiology Source Type: research
Conclusion: The incidence, age-distribution, locations and underlying disorders agree with published findings in pediatric populations. In our study, 87% of the children with VTE had either an identifiable acquired or genetic risk factor or a combination of both. Of those with a genetic risk factor, 13% had a recurrent VTE during the study period which indicates an even higher cumulative risk during childhood which emphasizes the need to consider prophylaxis in situations with increased risk of VTE. However, of those with recurrent VTE, no frequent acquired risk factor was identified.DisclosuresNo relevant conflicts of interest to declare.
Source: Blood - Category: Hematology Authors: Tags: 331. Pathophysiology of Thrombosis: Poster III Source Type: research
The past several years have been marked by confusion and controversy concerning whether estrogens are cardioprotective. The issue is of utmost public health importance because coronary heart disease (CHD) remains the leading cause of death among postmenopausal women. Fortunately, a unifying hypothesis has emerged that reproductive stage is a major determinant of the effect of estrogens on atherosclerosis progression, complications, and plaque vulnerability. Premenopausal Years: Premenopausal atherosclerosis progression seems to be an important determinant of postmenopausal atherosclerosis and thus the risk for CHD. Clea...
Source: Menopause - Category: OBGYN Tags: Commemorative Papers Source Type: research
More News: Cardiology | General Medicine | Heart | Heart Disease | Hormonal Therapy | Hormones | Netherlands Health | Women