Influence of Obesity and Type 2 Diabetes Mellitus on the Pharmacokinetics of Tramadol After Single Oral Dose Administration

ConclusionsNo significant differences were found in the pharmacokinetics of tramadol andO-desmethyltramadol, indicating that the opioid can be administered to overweight, obese and diabetic patients without dosage adjustment.

Source: European Journal of Drug Metabolism and Pharmacokinetics - February 18, 2019 Category: Drugs & Pharmacology Source Type: research