Neurogenic tumor: Teaching Points

Discussion –Peripheral nerve sheath tumors consist of neurofibromas and schwannomas in the benign category&malignant peripheral nerve sheath tumor (MPNST) in malignant category.Imaging features and signs that help to identify and characterize a nerve sheath tumor are, distribution of the tumor along a major nerve, an entering or exiting nerve sign, target sign, a fascicular sign and a split-fat sign.-         Distribution of the lesion along the course of the nerve is most important feature. Benign lesions may be located along the cutaneous or deep nerves, however, their malignant counterparts are seen most commonly along the major nerve trunk. Neurofibromas are seen most commonly in the head and neck regions, while schwannomas are more common in the lower extremity. The dumbbell shape is characteristically seen in paraspinal neurofibromas, in which intraspinal extension of the tumor causes widening of the neural canal.-         Entering or exiting nerve sign - Neurofibromas are characterized by fusiform enlargement of the nerve, with the tapered ends of the lesion toward the parent nerve. Schwannomas are usually located eccentrically in relation to the nerve. The plexiform variant of the neurofibroma causes a diffuse expansion and enlargement of the parent nerve resulting in a ‘bag of worms’ appearance on imaging as well as on gross pathological examination.-&...
Source: Sumer's Radiology Site - Category: Radiology Authors: Source Type: blogs

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A 26-year-old male patient presented with a painless swelling on the floor of mouth. The lesion started 2 months back after an incidence of trauma and gradually kept on increasing to its present condition. On intraoral examination, a solitary, well-defined, reddish swelling of 1 cm X 1 cm in diameter was detected on the floor of the mouth (Figure 1, Black arrow). The swelling was fluctuant, non-tender, non-pulsatile, non-reducible and soft in consistency. The fluctuant nature of the swelling ruled out fibroma, lipoma, and tumor of minor salivary gland while hemangioma was eliminated because of the non-pulsatile nature of the swelling.
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Clinical Communication to the Editor Source Type: research
[Tumors affecting the temporomandibular joint - a literature review]. Bull Cancer. 2020 Oct 12;: Authors: Schlund M, Roland-Billecart T, Aubert S, Nicot R Abstract Benign and malign tumors can affect the temporomandibular joint (TMJ) as any other articulation. Nevertheless, TMJ tumors are rare and mostly benign. Their clinical expression is varied including symptomatology similar to TMJ dysfunctional disorders, otologic or neurologic pathologies. In some cases, they remain totally asymptomatic. Hence, diagnosis is difficult since the symptomatology can be misleading with TMJ dysfunctional di...
Source: Bulletin du Cancer - Category: Cancer & Oncology Authors: Tags: Bull Cancer Source Type: research
The resection of distal airways obstructing tumours is a traditional indication of therapeutic bronchoscopy. Lung cancer is the most frequent cause of the obstruction. Takeout procedures of the benign tumours, endobronchial carcinoids and endobronchial metastases are considerably less frequent. These tumours can be removed completely, some of them definitively. Present work analyses experience with these tumours in one tertiary bronchological centre. During the period from 1993 to 2018, 29.121 bronchoscopies were performed and 124 benign tumours, 19 typical carcinoids (G1 NET) and 35 endobronchial metastases were removed. ...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Interventional pulmonology Source Type: research
This article describes a case of a 41-year-old male, a chronic smoker with an actively bleeding, ulcerated, solitary, firm lesion on the lateral border of the tongue which had bled thrice before. A differential diagnosis of pyogenic granuloma, haemangioma, fibroma, nerve sheath tumour, salivary gland tumour and malignancy was made and surgically excised. Histopathology of the excised specimen revealed a well-circumscribed lesion with spindle-shaped cells arranged in interlacing fascicles and with the help of immunohistochemical markers confirmed it to be a PEN. DISCUSSION: To our knowledge, this is the first descriptio...
Source: Malaysian Journal of Pathology - Category: Pathology Tags: Malays J Pathol Source Type: research
CONCLUSION:: In the deep palmar space of the hand, pathologies are closely associated with tendons, muscles, and neurovascular structures. Preoperative magnetic resonance imaging is helpful for the preoperative diagnosis, evaluating tumor extension, and successful surgical planning. Level of Evidence: IV Therapautic. PMID: 30955477 [PubMed - in process]
Source: Journal of Orthopaedic Surgery - Category: Orthopaedics Authors: Tags: J Orthop Surg (Hong Kong) Source Type: research
50 yr old lady presents for CEMRI with abdominal wall mass in USG with no history of trauma / fever / surgery.CEMRI shows – Large intense&heterogeneously enhancing altered signal intensity space occupying lesion involving left anterior parietes of abdominal wall extending from supraumbilical to pelvic region with areas of necrosis/ restricted diffusion /predominantly edematous signal components /rectus abdominis not separately identified / properitoneal fat stranding with no intraperitoneal extension / across midline /no definite skin ulceration /regional lymphadenopathy / air /MR demonstrable calcification ...
Source: Sumer's Radiology Site - Category: Radiology Authors: Source Type: blogs
Publication date: Available online 6 January 2019Source: European Journal of RadiologyAuthor(s): Pravin Mundada, Minerva Becker, Vincent Lenoir, Salvatore Stefanelli, Anne-Laure Rougemont, Jean Yves Beaulieu, Sana BoudabbousAbstractAlthough the nail is a small anatomical structure, it can be affected by various tumors and tumor-like conditions. Because of the distinctive nail anatomy, the clinical presentation of tumors is modified, thus rendering the diagnosis challenging. As nail biopsy and surgery are painful procedures associated with an increased risk of permanent onychodystrophy, pre-operative diagnosis is desirable....
Source: European Journal of Radiology - Category: Radiology Source Type: research
CONCLUSION: The most common OBNs were fibroma, papilloma, fibroblastoma, lipoma and hemangioma. Overall, the OBN presented common clinical features; however, in particular cases, there are some characteristics that can lead the professionals to the correct diagnosis. Nevertheless, in general, histopathological analysis must be performed to confirm diagnosis. Intraosseous tumors and large lesions may require imaging tests to help diagnosis. PMID: 30497661 [PubMed - as supplied by publisher]
Source: Acta Otorrinolaringologica Espanola - Category: ENT & OMF Authors: Tags: Acta Otorrinolaringol Esp Source Type: research
Authors: Miyake Y, Shinozuka K, Ueki K, Teraoka J, Zama M, Ogisawa S, Shinozaki Y, Aoki J, Yanagawa K, Shimizu O, Kaneko T, Tonogi M, Ohki H Abstract To better understand the clinical features of mass lesions of the tongue, we retrospectively evaluated frequency, recurrence rate, and complications in 296 patients who had undergone surgery for such lesions. The diagnoses were fibroma (43.6%), mucous cyst (14.2%), papilloma (11.8%), hemangioma (7.8%), granuloma (6.4%), lipoma (1.4%), schwannoma (1.0%), ectopic tonsil (0.7%), and other (13.2%). Recurrence was noted in two patients (0.7%). Twenty-two patients (7.4%) de...
Source: Journal of oral science - Category: Dentistry Tags: J Oral Sci Source Type: research
AbstractThe neck structures are located very superficially and are therefore easy to explore by ultrasound examination. Ultrasonography is crucial for the detection of neck pathologies in children. High-frequency probes (10 –15 MHz) are used for the ultrasound examination on the patient lying in supine decubitus and with their neck stretched out. The outcome of the exam depends mainly on the child’s cooperation—hence the need for warm sonographic gel and a comfortable cushion to place under the patient’s shoul ders. The complete scan of the neck includes the evaluation of the thyroid and saliva...
Source: Journal of Ultrasound - Category: Radiology Source Type: research
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