Perioperative Epidural Use and Risk of Delirium in Surgical Patients: A Secondary Analysis of the PODCAST Trial.

CONCLUSIONS: Postoperative epidural use was not associated with a reduced overall incidence of delirium. However, longitudinal analysis revealed reduced adjusted odds of experiencing an episode of delirium in the epidural group. Epidural use was also associated with reduced postoperative pain and opioid consumption. An appropriately designed follow-up study is warranted to further analyze the relationship among epidural use, postoperative delirium, and related outcomes.
PMID: 30768457 [PubMed - as supplied by publisher]

Source: Anesthesia and Analgesia - February 12, 2019 Category: Anesthesiology Authors: Vlisides PE, Thompson A, Kunkler BS, Maybrier HR, Avidan MS, Mashour GA, G P A, V K A, A BA, M B, R D, D A E, K E, B A F, H F, L N G, H G, A T G, J H, S K I, N S I, E J, A J, H H K, M S K, E L, A S M, S M, A M M, M R M, M M, P P, K O P, M R, E M R, E S, M Tags: Anesth Analg Source Type: research