A Novel Oral Glutarimide Derivative XC8 Suppresses Sephadex-Induced Lung Inflammation in Rats and Acute Asthma in Guinea Pigs.
CONCLUSION: The anti-asthmatic effect of XC8 is comparable to that of budesonide. Moreover, in contrast to budenoside treatment XC8 is capable of reducing of airway resistance and degranulating mast cell numbers in the airway tissue.
PMID: 30767739 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Biotechnology - Category: Biotechnology Authors: Ferko B, Romanova J, Rydlovskaya AV, Kromova TA, Proskurina OV, Amelina AN, Schmutz H, Renner A, Nebolsin VE Tags: Curr Pharm Biotechnol Source Type: research