Childhood Cancer Symptom Cluster: Leukemia and Health-Related Quality of Life.
Childhood Cancer Symptom Cluster: Leukemia and Health-Related Quality of Life. Oncol Nurs Forum. 2019 Mar 01;46(2):228-237 Authors: Rodgers CC, Hooke MC, Taylor OA, Koerner KM, Mitby PA, Moore IM, Scheurer ME, Hockenberry MJ, Pan W Abstract OBJECTIVES: To examine the relationship of the Childhood Cancer Symptom Cluster-Leukemia (CCSC-L) with health-related quality of life (HRQOL). SAMPLE & SETTING: 327 children receiving treatment for acute lymphoblastic leukemia from four pediatric oncology programs across the United States. METHODS & VARIABLES: Participants completed fatigue, sleep disturbance, pain, nausea, and depression symptom questionnaires at four time points; these symptoms comprised the CCSC-L. HRQOL was measured at the start of postinduction therapy and then at the start of maintenance therapy. Relationships between the CCSC-L and HRQOL scores were examined with longitudinal parallel-process modeling. RESULTS: The mean HRQOL significantly increased over time (p
In conclusion, this study elucidated that combination of cisplatin and XAV-939 exerted cytotoxic and genotoxic effect to abrogate CSC mediated chemoresistance in HNSCC in synergistic manner.
Publication date: Available online 17 August 2019Source: Revista Clínica Española (English Edition)Author(s): J. Masip, J.R. Germà LluchAbstractRecent epidemiological studies have shown that alcohol consumption can increase the risk of arterial hypertension, atrial fibrillation and gastrointestinal and breast cancer. Various sectors are therefore promoting abstinence from alcohol. However, light alcohol consumption has once again been shown to reduce the risk of myocardial infarction and diabetes but with an unclear effect on cerebrovascular disease. The decision to consume alcohol should therefore be ...
Publication date: Available online 17 August 2019Source: Surgery (Oxford)Author(s): Tim LaneAbstractUpper tract transitional cell carcinoma is a lethal disease with half the patients dead within 5 years of diagnosis. Unlike urothelial tumours arising in the bladder, the disease is more likely to be invasive at the time of diagnosis and in part reflects the poorer prognosis. It is a biologically aggressive disease with a high chance of recurrence even after local control. Diagnosis is made by a combination of upper tract imaging, urine cytology and ureteroscopic biopsy. Organ-confined disease is amenable to radical surgery,...
This article aims to summarize the current knowledge of prostate cancer and treatment options available.
Publication date: Available online 17 August 2019Source: Surgery (Oxford)Author(s): Jameel Mushtaq, Ramesh Thurairaja, Rajesh NairAbstractUrothelial carcinoma of the bladder is the most common malignancy affecting the urinary tract. This review examines the current standards in the diagnosis and management of this disease. Cystoscopy and urine cytology remain important tools in the diagnosis and follow-up of bladder cancer. Alternatives include photodynamic diagnosis, narrow band imaging and professional image enhancement which may improve detection of tumours. En-bloc resection using either laser or electrocautery shows p...
ConclusionOnly a few cases of penile FG have been reported. Early debridement of all necrotic tissue is the golden rule.
ConclusionsWe present the rare case of a patient with surgically resected locally advanced rectal cancer who demonstrated an impressive pCR with preoperative chemotherapy, which included FOLFOX plus bevacizumab.
CONCLUSIONWe present a case of SCC in the anal canal with liver metastasis presenting as a hepatic pseudocyst.
Wanted your opinions on your management. If you have someone come in with mild pancreatitis unknown etiology (full work up normal) with no abnormal labs other than the lipase being>5000. Vitals stable. APACHE II on admission 3. And patient wants to eat the next day with pain improved despite lipase being still>5000. Would you initiate early refeeding or would you wait a while?
Question: Are we diluting the prestige and value of ACGME-accredited Pain fellowships by allowing alternative venues of interventional training? https://www.spine.org/Portals/0/Assets/Downloads/Education/ISMMFellowshipDirectory.pdf "WHAT DISTINGUISHES NASS ISMM FELLOWSHIPS FROM PAIN FELLOWSHIPS? The primary focus of NASS-recognized ISMM fellowships is the clinical assessment and treatment of patients with spine and musculoskeletal conditions. The fellowships... New NASS-approved vs ACGME-accredited Spine/Pain Fellowships?