Association betweenPNPLA3rs738409, polymorphism, decreased kidney function in postmenopausal type 2, diabetic women with or without non-alcoholic fatty liver disease.

CONCLUSION: - Regardless of the presence of NAFLD, in post-menopausal women with T2DM, the G/G genotype of rs738409 in the PNPLA3 gene was independently associated with lower eGFRCKD-EPI and higher prevalence of CKD.
PMID: 30763699 [PubMed - as supplied by publisher]

Source: Diabetes and Metabolism - February 11, 2019 Category: Endocrinology Authors: Mantovani A, Zusi C, Sani E, Colecchia A, Lippi G, Zaza G, Valenti L, Byrne CD, Maffeis C, Bonora E, Targher G Tags: Diabetes Metab Source Type: research